巨细胞病毒感染肺炎婴幼儿听力检测结果分析

发布时间：2018-06-16 10:18

本文选题：人巨细胞病毒 + 肺炎　；参考：《听力学及言语疾病杂志》2017年06期

【摘要】：目的探讨人巨细胞病毒(human cytomegalovirus,HCMV,简称CMV)感染肺炎婴幼儿的听力学特点。方法以确诊为CMV感染肺炎婴幼儿(CMV感染组)115例(230耳)为研究对象,并选取同期非CMV感染肺炎婴幼儿(非CMV感染组)115例(230耳)以及健康婴幼儿115例(230耳)(对照组),分别进行听性脑干反应(auditory brainsen response,ABR)、声导抗测试,比较三组的结果及听力随访情况。结果CMV感染组50耳(21.74%)、非CMV感染组34耳(14.78%)、健康对照组17耳(7.39%)ABR波V阈值30dB nHL(P0.05);CMV感染组感音神经性听力损失检出率(16.96%,39/230)高于非CMV感染组(6.52%,15/230)和健康对照组(1.74%,4/230)(P0.05);CMV感染组(8.70%,20/230)、非CMV感染组(12.17%,28/230)声导抗异常耳均高于健康对照组(2.61%,6/230),CMV感染组、非CMV感染组组间差异无统计学意义(P0.05);随访3年,CMV感染组有3例感音神经性听力损失者听力恢复正常,各组其余感音神经性听力损失患儿听力无改善,各组传导性听力损失者均恢复正常。结论 CMV感染肺炎婴幼儿感音神经性聋发病率高,CMV感染肺炎容易导致中耳功能异常引起ABR反应阈升高;对于CMV感染肺炎婴幼儿需要行综合听力学检测且长期随访。
[Abstract]:Objective to investigate the audiological characteristics of infantile pneumonia infected with human cytomegalovirus virus (CMV). Methods 115 cases (230 ears) of infantile pneumonia with CMV infection were studied. At the same time, the infants and infants with non-CMV-infected pneumonia (115 non-CMV-infected infants) and healthy infants (control group) were tested with auditory brainstem response (auditory brainsen responseABR) and acoustic impedance respectively. The results of the three groups were compared and the hearing follow-up was compared. Results 50 ears of CMV infection group (50 ears) and 34 ears of non-CMV infection group (14.78 ears), 17 ears of healthy control group (17 ears) with ABR wave V threshold of 30 dB nHLR P0.05 + CMV infection group were higher than those of non-CMV infection group (6.52% 15230) and healthy control group (1.74% 230P 0.05% CMV infection group 8.70% 230). The abnormal acoustic impedance was higher in the abnormal acoustic impedance group than in the control group (2.61% vs 2.61%). There was no significant difference between the groups with non-CMV infection (P 0.05), 3 patients with sensorineural hearing loss in CMV infection group recovered to normal for 3 years, and the hearing of other children with sensorineural hearing loss did not improve. All the patients with conductive hearing loss returned to normal. Conclusion the incidence of sensorineural hearing loss in infants with CMV infection is high. CMV infection pneumonia may lead to abnormal middle ear function and increase ABR response threshold.
【作者单位】：重庆医科大学附属儿童医院耳鼻咽喉科;儿童发育疾病研究教育部重点实验室;儿童发育重大疾病国家国际科技合作基地;重庆医科大学附属儿童医院呼吸科;
【分类号】：R764.04

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