感染性角膜炎的病原菌谱回顾性分析

发布时间：2018-07-31 17:23

【摘要】：目的分析感染性角膜炎的病原菌谱特征,提供感染性角膜炎早期诊断及治疗的依据。方法收集云南省第二人民医院眼科2011年1月至2015年12月,确诊为感染性角膜炎患者的角膜溃疡刮片或术中切除的角膜溃疡组织标本资料,对普通细菌及真菌培养的结果进行回顾性分析,评价感染病原菌谱的分布特征及危险因素。结果 1 046例(只眼)的角膜溃疡标本培养阳性率为35.3%。分离的病原菌以真菌为主(53.1%),其次是革兰阳性球菌(31.2%)、革兰阴性杆菌(11.1%)及革兰阳性杆菌(4.6%);而真菌中以镰刀霉属构成比最高,为69.4%,其次是曲霉属(21.9%);革兰阳性球菌以凝固酶阴性葡萄球菌为主(50.4%)。结论该院感染性角膜炎以真菌性角膜炎多见,主要病原菌是丝状真菌,以镰刀霉属的感染为主。
[Abstract]:Objective to analyze the characteristics of pathogenic bacteria in infectious keratitis and to provide evidence for early diagnosis and treatment of infectious keratitis. Methods from January 2011 to December 2015, corneal ulcer scraping or excision of corneal ulcer tissue samples from patients with infectious keratitis were collected from the second people's Hospital of Yunnan Province from January 2011 to December 2015. The results of culture of common bacteria and fungi were analyzed retrospectively to evaluate the distribution characteristics and risk factors of pathogenic bacteria. Results the positive rate of corneal ulcer specimen culture in 1 046 cases was 35. 3%. The main pathogens were fungi (53.1%), Gram-positive cocci (31.2%), Gram-negative bacilli (11.1%) and Gram-positive bacilli (4.6%). It was 69.4%, followed by Aspergillus (21.9%), Gram-positive coccus was coagulase negative staphylococcus (50.4%). Conclusion fungal keratitis is the most common infectious keratitis in our hospital. The main pathogen is filamentous fungi and the infection of Fusarium is the main pathogen.
【作者单位】：云南省第二人民医院检验科;
【分类号】：R772.21

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