颈内动脉与原发性开角型青光眼的相关性研究

发布时间：2018-08-17 15:31

【摘要】：目的:通过对原发性开角型青光眼患者行颈内动脉彩色多普勒超声和全自动视野、光学相干断层扫描(OCT)检查,探讨颈内动脉与原发性开角型青光眼视神经纤维层厚度、视野的相关性。方法:本文将新疆医科大学第一附属医院眼科2012年6月至2016年12月期间94例(188只眼)纳入研究。所有患者均行颈内动脉彩色多普勒超声、光学相干断层扫描(OCT)及全自动视野检查,将颈内动脉血管内径、血管搏动指数(PI)、血管阻力指数(RI)、收缩期峰值血流速度(PSV)、舒张末期血流速度(EDV)和各象限视网膜神经纤维层(RNFL)厚度、视野指数(VFI)、平均偏差(MD)、模式标准偏差(PSD)进行统计学分析。结果:原发性开角型青光眼患者的颈内动脉内径和下方RNFL有相关性(P0.05);颈内动脉PI、RI与上方、下方、颞侧RNFL有相关性(P0.05);颈内动脉内径、PI、RI及PSV和MD有相关性(P0.05);颈内动脉收缩期血流速度和PSD有相关性(P0.05);原发性开角型青光眼颈内动脉内径、PI、RI及EDV和VFI、PSD无明显相关性(P0.05)。结论:原发性开角型青光眼患者颈内动脉内径、搏动指数、血管阻力和收缩压血流速度会影响患者的视神经纤维层厚度和视野损害程度。
[Abstract]:Objective: to investigate the thickness of the optic nerve layer between the internal carotid artery and primary open-angle glaucoma by using color Doppler ultrasound, automatic visual field and optical coherence tomography (OCT) in patients with primary open-angle glaucoma. The relevance of visual field. Methods: 94 cases (188 eyes) of ophthalmology in the first affiliated Hospital of Xinjiang Medical University from June 2012 to December 2016 were included in the study. All patients underwent color Doppler ultrasound, optical coherence tomography (OCT) and automatic visual field examination. Pulsatile index (PI), vascular resistance index (RI),) peak systolic velocity (PSV), end-diastolic velocity (EDV) and retinal nerve fiber layer (RNFL) thickness of each quadrant and visual field index (VFI),) mean deviation (MD), model standard deviation (PSD) were statistically analyzed. Results: there was a correlation between the internal diameter of the internal carotid artery and the inferior RNFL in patients with primary open-angle glaucoma (P0.05). There was correlation between RNFL of temporal side (P0.05), RI of internal carotid artery and PSV and MD (P0.05); blood flow velocity of internal carotid artery was correlated with PSD (P0.05); the diameter of internal carotid artery of primary open-angle glaucoma had no significant correlation with EDV and VFII-PSD (P0.05). Conclusion: the thickness of optic nerve fiber layer and the degree of visual field damage are affected by the internal diameter of internal carotid artery pulsatility index vascular resistance and blood flow velocity of systolic blood pressure in patients with primary open angle glaucoma.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R775

【相似文献】