炎性肠病患者病情与脉络膜厚度的关系

发布时间：2018-09-19 15:08

【摘要】：目的通过分析不同病情的炎性肠病(inflammatory bowel disease,IBD)与脉络膜厚度的关系,探讨将脉络膜厚度用于评价IBD病情的可行性。方法光学相干断层扫描仪的增强深部扫描技术对50例(100眼)不同病情的IBD患者的脉络膜厚度进行测量,包括23例溃疡性结肠炎(ulcerative colitis,UC)和27例克罗恩病(Crohn’s disease,CD)患者,另有48名(96眼)健康志愿者作为对照被纳入研究。结果与正常志愿者的黄斑中心凹下脉络膜厚度(294.37±35.04)μm相比较,UC患者中病情为重度者的黄斑中心凹下脉络膜厚度(349.28±76.57)μm增加显著(P0.05),CD患者中病情为中度者及重度者的黄斑中心凹下脉络膜厚度[(326.71±59.71)μm、(354.24±66.34)μm]也均增加显著(均为P0.05)。结论脉络膜厚度可作为评价IBD患者尤其是CD患者病情严重程度的指标。
[Abstract]:Objective to explore the feasibility of using choroidal thickness to evaluate the condition of IBD by analyzing the relationship between (inflammatory bowel disease,IBD (inflammatory bowel disease) and choroidal thickness. Methods the choroidal thickness of 50 patients (100 eyes) with IBD, including 23 patients with ulcerative colitis (ulcerative colitis,UC) and 27 patients with Crohn's disease (Crohn's disease,CD), was measured by enhanced deep scanning with optical coherence tomography (OCT), including 23 patients with ulcerative colitis (ulcerative colitis,UC) and 27 patients with Crohn's disease (Crohn's disease,CD). Another 48 healthy volunteers (96 eyes) were included as controls. Results compared with normal volunteers, the thickness of subfoveal choroid in patients with severe macular central fovea (349.28 卤76.57) 渭 m increased significantly (P0.05) in patients with moderate macular central fovea choroidal thickness (294.37 卤35.04) 渭 m compared with those in patients with severe macular central fovea (294.37 卤35.04) 渭 m (P0.05). The thickness of subconcave choroid [(326.71 卤59.71) 渭 m, (354.24 卤66.34) 渭 m] also increased significantly (P0.05). Conclusion choroidal thickness can be used as an index to evaluate the severity of IBD, especially CD.
【作者单位】：西安市第三医院眼科;西安市第三医院消化内科;
【分类号】：R574.62;R771.3

【相似文献】