青少年近视性屈光参差患者长期配戴角膜塑形镜效果观察
发布时间：2018-10-16 10:34
【摘要】：目的探讨青少年屈光参差患者配戴角膜塑形镜3年后眼轴、中央角膜厚度及角膜内皮细胞密度的变化。设计回顾性病例系列。研究对象2011-2013年在北京同仁验光配镜中心验配角膜塑形镜且连续戴镜3年以上、按时复诊的近视性屈光参差青少年患者21例(42眼)。方法依近视度数将患眼分为高度数眼组(高于-3.00 D)及低度数眼组(低于等于-3.00 D),观察并比较戴镜前及戴镜6个月、1年、2年、3年后各组眼轴、中央角膜厚度及角膜内皮细胞密度等参数的变化。主要指标眼轴、中央角膜厚度、角膜内皮细胞密度。结果戴镜前及戴镜6个月、1年、2年、3年后高度数眼组眼轴分别为(25.16±0.78)mm、(25.27±0.81)mm、(25.43±0.91)mm、(25.50±0.85)mm和(25.64±0.87)mm,低度数眼组眼轴分别为(24.13±0.99)mm、(24.38±0.96)mm、(24.49±1.00)mm、(24.71±0.94)mm和(24.88±1.01)mm,双眼眼轴均随时间增长(F=48.2;P=0.000),高度数眼组眼轴更长(F=10.186;P=0.003)。各时间点眼轴差异量分别为(1.03±0.45)mm、(0.90±0.40)mm、(0.85±0.39)mm、(0.79±0.41)mm及(0.76±0.44)mm,戴镜后双眼眼轴差异量逐渐缩小(F=9.494;P=0.000)。戴镜前及戴镜6个月、1年、2年、3年后高度数眼组角膜内皮细胞密度分别为(3362.57±278.73)个/mm~2、(3393.67±325.88)个/mm~2、(3333.76±288.72)个/mm~2、(3276.90±240.49)个/mm~2及(3259.71±357.41)个/mm~2,低度数眼组角膜内皮细胞密度分别为(3365.62±352.75)个/mm~2、(3387.62±363.57)个/mm~2、(3314.05±270.12)个/mm~2、(3290.71±327.64)个/mm~2及(3307.05±357.12)个/mm~2,随着戴镜时间延长,双眼角膜内皮细胞密度呈下降趋势(F=4.386;P=0.006),双眼间比较无统计学差异(F=0.007,P=0.932)。戴镜前及戴镜6个月、1年、2年、3年后高度数眼组中央角膜厚度分别为(548.81±28.34)μm、(531.43±33.30)μm、(526.05±30.84)μm、(523.38±27.54)μm和(525.29±27.92)μm,低度数组眼中央角膜厚度分别为(549.76±28.72)μm、(536.90±26.51)μm、(534.24±27.67)μm、(534.19±25.84)μm及(531.76±27.16)μm,戴镜后6个月中央角膜厚度下降,以后无变化(F=56.843;P=0.000)。结论青少年近视性屈光参差患者长期配戴角膜塑形镜后双眼眼轴差距缩小。角膜塑形效果于戴镜6个月内稳定。
[Abstract]:Objective to investigate the changes of corneal axis, central corneal thickness and corneal endothelial cell density in juvenile anisometropia patients after wearing corneal plastic lens for 3 years. Design retrospective case series. Participants 21 cases (42 eyes) of myopic anisometropia were examined in Beijing Tongren optometry Center from 2011 to 2013. Methods according to the degree of myopia, the eyes were divided into high degree group (> -3.00D) and low degree eye group (< -3.00 D),) and compared with each group after 6 months, 1 year, 2 years and 3 years after wearing mirror. Changes of central corneal thickness and corneal endothelial cell density. Main outcome measures: eye axis, central corneal thickness, corneal endothelial cell density. 缁撴灉鎴撮暅鍓嶅強鎴撮暅6涓湀,1骞，
本文编号：2274085
[Abstract]:Objective to investigate the changes of corneal axis, central corneal thickness and corneal endothelial cell density in juvenile anisometropia patients after wearing corneal plastic lens for 3 years. Design retrospective case series. Participants 21 cases (42 eyes) of myopic anisometropia were examined in Beijing Tongren optometry Center from 2011 to 2013. Methods according to the degree of myopia, the eyes were divided into high degree group (> -3.00D) and low degree eye group (< -3.00 D),) and compared with each group after 6 months, 1 year, 2 years and 3 years after wearing mirror. Changes of central corneal thickness and corneal endothelial cell density. Main outcome measures: eye axis, central corneal thickness, corneal endothelial cell density. 缁撴灉鎴撮暅鍓嶅強鎴撮暅6涓湀,1骞，
本文编号：2274085
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