特发性黄斑裂孔OCT影像与术后早期视力恢复的相关性研究
发布时间：2018-11-15 22:09
【摘要】：目的研究特发性黄斑裂孔(idiopathic macular holes,IMH)患者术前光学相干断层扫描技术(optical coherence tomography,OCT)测量的相关参数与术后早期视力恢复的相关性。方法收集24例(25眼)IMH患者,均行玻璃体切割+内界膜剥离+玻璃体内注气术,术前、术后12周均行最佳矫正视力(best corrected visual acuity,BCVA)检查,术前1周内OCT影像上直接测量裂孔最大高度,通过Image-Pro Plus 6.0软件测量黄斑裂孔最小径、基底径及外界膜光感受器断裂点与视网膜色素上皮层的最大垂直高度,并计算黄斑孔指数(macular hole index,MHI)、牵拉孔指数(tractional hole index,THI)、黄斑孔指数'(macular hole index',MHI')及牵拉孔指数'(tractional hole index',THI'),应用SPSS 22.0软件包进行Spearman相关性分析,得出各参数与术后12周时BCVA的相关性,受试者工作特征曲线拟合分析得出MHI、THI、MHI'、THI'界值。结果IMH患者术后12周BCVA较术前明显提高且差异有统计学意义(P=0.000)。相关性分析结果表明:术后12周BCVA与术前MHI、THI、MHI'、THI'具有相关性(均为P0.05)。MHI≥0.705组术后12周时BCVA平均为0.297,好于MHI0.705组的0.103(P=0.023);THI≥1.425组术后12周时BCVA平均为0.288,好于THI1.425组的0.163(P=0.001)。结论THI≥1.425或MHI≥0.705者术后12周时能获得较好的BCVA,可作为预测IMH患者术后早期视力恢复情况的指标。
[Abstract]:Objective to study the correlation between preoperative optical coherence tomography (optical coherence tomography,OCT) and early postoperative visual acuity in patients with idiopathic macular hole (idiopathic macular holes,IMH). Methods Twenty-four patients (25 eyes) with IMH underwent intravitreal gas injection by vitrectomy with internal boundary membrane dissection. The best corrected visual acuity (best corrected visual acuity,BCVA) was performed before and 12 weeks after operation. The maximum height of the hiatus was measured directly on OCT images within 1 week before operation. The minimum diameter of macular hole, the basal diameter and the maximum vertical height of the outer membrane photoreceptor and the retinal pigment epithelium were measured by Image-Pro Plus 6.0 software. The macular pore index (macular hole index,MHI), the drag hole index (tractional hole index,THI), the macular pore index'(macular hole index',MHI') and the pull hole index'(tractional hole index',THI') were calculated. The correlation analysis of Spearman with SPSS 22.0 software package was carried out, and the correlation between each parameter and BCVA at 12 weeks after operation was obtained. The threshold value of MHI,THI,MHI',THI' was obtained by fitting the operating characteristic curve of the subjects. Results BCVA was significantly higher in IMH patients 12 weeks after operation than that before operation (P0. 000). The results of correlation analysis showed that there was a correlation between BCVA and preoperative MHI,THI,MHI',THI' at 12 weeks postoperatively (P0.05). MHI 鈮，
本文编号：2334537
[Abstract]:Objective to study the correlation between preoperative optical coherence tomography (optical coherence tomography,OCT) and early postoperative visual acuity in patients with idiopathic macular hole (idiopathic macular holes,IMH). Methods Twenty-four patients (25 eyes) with IMH underwent intravitreal gas injection by vitrectomy with internal boundary membrane dissection. The best corrected visual acuity (best corrected visual acuity,BCVA) was performed before and 12 weeks after operation. The maximum height of the hiatus was measured directly on OCT images within 1 week before operation. The minimum diameter of macular hole, the basal diameter and the maximum vertical height of the outer membrane photoreceptor and the retinal pigment epithelium were measured by Image-Pro Plus 6.0 software. The macular pore index (macular hole index,MHI), the drag hole index (tractional hole index,THI), the macular pore index'(macular hole index',MHI') and the pull hole index'(tractional hole index',THI') were calculated. The correlation analysis of Spearman with SPSS 22.0 software package was carried out, and the correlation between each parameter and BCVA at 12 weeks after operation was obtained. The threshold value of MHI,THI,MHI',THI' was obtained by fitting the operating characteristic curve of the subjects. Results BCVA was significantly higher in IMH patients 12 weeks after operation than that before operation (P0. 000). The results of correlation analysis showed that there was a correlation between BCVA and preoperative MHI,THI,MHI',THI' at 12 weeks postoperatively (P0.05). MHI 鈮，
本文编号：2334537
本文链接：https://www.wllwen.com/yixuelunwen/wuguanyixuelunwen/2334537.html
最近更新
教材专著
