睡眠状态对夜间眼压影响的初步分析
发布时间：2018-12-29 13:33
【摘要】：目的:探索睡眠状态对夜间眼压的影响。方法:对正常人共20例(40只眼),2014年9月至11月来院就诊的高眼压症人群37例及抗青光眼术后高眼压患者23例,各自分夜间单次测量及自身对照夜间多次测量,对入选标准人群第一天只测凌晨3:30眼压,第二天从7:30开始,每间隔两小时一次,收集24小时眼压,对比研究组及自身对照组凌晨3:30眼压,用SPSS18.0软件做统计学分析.结果:1.正常受试人群20例(40眼)平均年龄31.2±8.7(24-41)岁参加了这项研究。第一天习惯性睡眠状态下,凌晨3:30眼压在14.2±3.4(11-17)mm Hg,第二天夜间多次眼压测量的凌晨3:30眼压在15.9±4.9(11-22)mm Hg。比较两组凌晨3:30眼压有统计显著差异(t=-2.021,P0.05)。2.高眼压症受试人群37例(62眼)平均年龄41.1±18.6(27-60)岁参加了这项研究。第一天习惯性睡眠状态下,凌晨3:30眼压在20.2±3.0(15-26)mm Hg,第二天夜间多次眼压测量的凌晨3:30眼压在21.9±4.0(16-28)mm Hg。比较两组凌晨3:30眼压有统计显著差异(t=-5.150,P0.05)。3.抗青光眼术后高眼压患者23例(36眼)平均年龄年龄分58.1±25.6(33-74)岁参加了这项研究。第一天习惯性睡眠状态下,凌晨3:30眼压在20.2±3.0(15-24)mm Hg,第二天夜间多次眼压测量的凌晨3:30眼压在23.9±5.0(16-30)mm Hg。比较两组凌晨3:30眼压有统计显著差异(t=-9.203,P0.05)。4.对比三组研究结果,得出正常受试人群(t=-2.021,P0.05),高眼压症受试人群(t=-5.150,P0.05),抗青光眼术后高眼压患者(t=-9.203,P0.05),多次眼压测量对夜间眼压的影响抗青光眼术后高眼压患者更明显.结论:(1)夜间多次眼压测量影响睡眠状态后可导致眼压升高。(2)单次夜间眼压测量较夜间多次眼压测量可能更为准确。
[Abstract]:Objective: to explore the effect of sleep state on nocturnal intraocular pressure (IOP). Methods: a total of 20 normal subjects (40 eyes), 37 patients with IOP and 23 patients with IOP after anti-glaucoma surgery were enrolled in our hospital from September to November 2014. The intraocular pressure was measured only at 3:30 on the first day and every two hours at 7:30 on the first day. The intraocular pressure was collected for 24 hours. The intraocular pressure was compared between the study group and the control group at 3:30 in the morning. Use SPSS18.0 software to do statistical analysis. Results: 1. The average age of 20 normal subjects (40 eyes) was 31.2 卤8.7 (24-41) years. On the first day of habitual sleep, the intraocular pressure at 3:30 was 14.2 卤3.4 (11-17) mm Hg,) and the intraocular pressure was 15.9 卤4.9 (11-22) mm Hg.) at 3:30. There was significant difference in IOP between the two groups at 3:30 in the morning (t = 2. 021, P 0.05). An average age of 41.1 卤18.6 (27-60) years in 37 patients (62 eyes) with ocular hypertension took part in the study. On the first day of habitual sleep, the intraocular pressure at 3:30 was 20.2 卤3.0 (15-26) mm Hg,) and the intraocular pressure was 21.9 卤4.0 (16-28) mm Hg.) at 3:30. There was significant difference in IOP between the two groups at 3:30 in the morning (t = -5.150, P 0.05). The mean age of 23 patients (36 eyes) with high intraocular pressure after glaucoma surgery was 58.1 卤25.6 (33-74) years. On the first day of habitual sleep, the intraocular pressure of 23.9 卤5.0 (16-30) mm Hg.) was measured at 23.9 卤5.0 (16-30) mm Hg.) at 3:30 (15-24) mm Hg,). There was significant difference in IOP between the two groups at 3:30 in the morning (tr -9.203 P 0.05). By comparing the results of the three groups, the results showed that the normal subjects (tr-2.021), the patients with high IOP (t-5. 150), the patients with high intraocular pressure after anti-glaucoma (t-9. 203), the patients with high intraocular pressure (t-9. 203), and the patients with high intraocular pressure (t-5-5. 150), Effects of multiple intraocular pressure measurements on nocturnal intraocular pressure in patients with high intraocular pressure after anti-glaucoma surgery. Conclusion: (1) multiple intraocular pressure measurements at night may lead to the elevation of intraocular pressure after affecting sleep state. (2) single night intraocular pressure measurement may be more accurate than multiple nocturnal intraocular pressure measurements.
【学位授予单位】：南昌大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R775
本文编号：2394893
[Abstract]:Objective: to explore the effect of sleep state on nocturnal intraocular pressure (IOP). Methods: a total of 20 normal subjects (40 eyes), 37 patients with IOP and 23 patients with IOP after anti-glaucoma surgery were enrolled in our hospital from September to November 2014. The intraocular pressure was measured only at 3:30 on the first day and every two hours at 7:30 on the first day. The intraocular pressure was collected for 24 hours. The intraocular pressure was compared between the study group and the control group at 3:30 in the morning. Use SPSS18.0 software to do statistical analysis. Results: 1. The average age of 20 normal subjects (40 eyes) was 31.2 卤8.7 (24-41) years. On the first day of habitual sleep, the intraocular pressure at 3:30 was 14.2 卤3.4 (11-17) mm Hg,) and the intraocular pressure was 15.9 卤4.9 (11-22) mm Hg.) at 3:30. There was significant difference in IOP between the two groups at 3:30 in the morning (t = 2. 021, P 0.05). An average age of 41.1 卤18.6 (27-60) years in 37 patients (62 eyes) with ocular hypertension took part in the study. On the first day of habitual sleep, the intraocular pressure at 3:30 was 20.2 卤3.0 (15-26) mm Hg,) and the intraocular pressure was 21.9 卤4.0 (16-28) mm Hg.) at 3:30. There was significant difference in IOP between the two groups at 3:30 in the morning (t = -5.150, P 0.05). The mean age of 23 patients (36 eyes) with high intraocular pressure after glaucoma surgery was 58.1 卤25.6 (33-74) years. On the first day of habitual sleep, the intraocular pressure of 23.9 卤5.0 (16-30) mm Hg.) was measured at 23.9 卤5.0 (16-30) mm Hg.) at 3:30 (15-24) mm Hg,). There was significant difference in IOP between the two groups at 3:30 in the morning (tr -9.203 P 0.05). By comparing the results of the three groups, the results showed that the normal subjects (tr-2.021), the patients with high IOP (t-5. 150), the patients with high intraocular pressure after anti-glaucoma (t-9. 203), the patients with high intraocular pressure (t-9. 203), and the patients with high intraocular pressure (t-5-5. 150), Effects of multiple intraocular pressure measurements on nocturnal intraocular pressure in patients with high intraocular pressure after anti-glaucoma surgery. Conclusion: (1) multiple intraocular pressure measurements at night may lead to the elevation of intraocular pressure after affecting sleep state. (2) single night intraocular pressure measurement may be more accurate than multiple nocturnal intraocular pressure measurements.
【学位授予单位】：南昌大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R775
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