物理与药物治疗对持续性变应性鼻炎的疗效探讨

发布时间：2019-01-01 17:59

【摘要】：目的:探讨物理治疗结合药物治疗对持续性变应性鼻炎(allergic rhinitis,AR)的疗效。方法:将192例患者随机分为3组,A组72例,B组70例,C组50例,AB组分别在鼻内镜下行聚焦超声与射频消融治疗,术后应用糠酸莫米松鼻喷雾剂喷鼻1个月,C组应用糠酸莫米松鼻喷雾剂+西替利嗪片1个月。治疗后随访6个月,用计分法进行疗效评价。结果:总有效率分别为1个月:A组97.2%,B组97.1%,C组96.0%;6个月:A组90.3%,B组87.1%,C组64.0%。3组治疗后1个月症状评分比较,疗效相当,无统计学意义(P0.05);3组患者治疗后6个月有效率比较,差异具有显著的统计学意义,A组与B组有效率均高于C组(P0.05);治疗后喷嚏症状评分比较,A组优于B组,差异有显著性(P0.05),但鼻塞评分比较,B组优于A组,差异有显著性(P0.05)。结论:两种物理治疗方法联合糠酸莫米松治疗持续性AR,前者改善喷嚏症状优于后者,但改善鼻塞症状不如后者。药物治疗持续性AR的远期疗效不及物理治疗联合药物治疗。聚焦超声联合糠酸莫米松治持续性AR,值得推广,尤其适合中-重度持续性AR患者。
[Abstract]:Objective: to investigate the effect of physiotherapy combined with drug therapy on persistent allergic rhinitis (allergic rhinitis,AR). Methods: 192 patients were randomly divided into three groups: group A (n = 72), group B (n = 70) and group C (n = 50). AB group was treated with focused ultrasound and radiofrequency ablation respectively. Group C was treated with momethasone furoate nasal spray cetirizine for 1 month. Patients were followed up for 6 months and evaluated with scoring method. Results: the total effective rate was 1 month. Six months: group A 90.3 and group B 87.1and group C 64.0.3 after treatment, the symptom score was comparable, there was no statistical significance (P0.05); The effective rate of group A and group B were significantly higher than that of group C (P0.05). After treatment, the sneeze symptom score in group A was better than that in group B, the difference was significant (P0.05), but the score of nasal congestion in group B was better than that in group A (P0.05). Conclusion: two physiotherapy methods combined with momethasone furoate in the treatment of persistent AR, are superior to the latter in improving sneezing symptoms, but not in improving nasal congestion. The long-term efficacy of drug therapy for persistent AR is not as good as physical therapy combined with drug therapy. The treatment of persistent AR, with focused ultrasound combined with momethasone furoate is worth popularizing, especially in patients with moderate to severe persistent AR.
【作者单位】：川北医学院第二临床学院·南充市中心医院耳鼻咽喉科;南充市第五人民医院五官科医院;
【基金】：四川省教育厅基金资助(13ZB0241) 川北医学院博士科研启动基金(CBY13-QD-08) 南充市科学技术和知识产权局(16YFZJ0021)
【分类号】：R765.21

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