家族性渗出性玻璃体视网膜病变临床研究

发布时间：2019-01-04 11:54

【摘要】：目的观察新生儿时期的家族性渗出性玻璃体视网膜病变(Familial Exudative Vitreoretinopathy,FEVR)的发病状况及临床特征。方法回顾性分析于2014年1月至2016年3月在我院行Retcam眼底筛查中被临床诊断为FEVR的103例169眼的临床资料。结果 16446例新生儿中发现FEVR病变103例,发生率为0.63%。其中有3例(2.91%)是早产或低出生体重儿。103例169眼中,1期156眼(92.31),2期9眼(5.33%),4期4眼(2.36%),3期及5期均未见(0%)。大多数(92.31%)患者病情好转或趋于稳定,随访观察,需要激光治疗的5例9眼,占5.33%。结论(1)FEVR和早产儿视网膜病变的临床特征非常相似,其鉴别诊断需进一步完善。(2)大部分患儿属于FEVR的早期,暂不需治疗,但也有部分需要尽快进一步治疗,挽救患儿视力。
[Abstract]:Objective to observe the incidence and clinical features of familial exudative vitreoretinopathy (Familial Exudative Vitreoretinopathy,FEVR) in neonates. Methods from January 2014 to March 2016, we retrospectively analyzed the clinical data of 169 eyes of 103 cases diagnosed as FEVR by Retcam fundus screening in our hospital from January 2014 to March 2016. Results 103 cases of FEVR were found in 16446 neonates, the incidence was 0.63. Among them, 3 cases (2.91%) were premature or low birth weight infants. In 103 cases (169 eyes), 156 eyes (92.31 eyes) were in stage 1, 9 eyes (5.33%) in stage 2, 4 eyes (2.36%) in stage 4, and none in stage 3 or stage 5 (0%). The majority of the patients (92.31%) were better or more stable. Follow-up observation showed that 5 cases (9 eyes) were in need of laser treatment, accounting for 5.33 eyes. Conclusion (1) the clinical features of FEVR and premature retinopathy are very similar, and the differential diagnosis needs further improvement. (2) most of the children belong to the early stage of FEVR and do not need treatment, but some of them need further treatment as soon as possible. Save the child's eyesight.
【作者单位】： 广东省珠海市妇幼保健院眼科;深圳市眼科医院;
【分类号】：R774.1
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