老年突发性耳聋患者血清可溶性血管细胞黏附分子-1水平及其影响因素

发布时间：2019-01-25 20:19

【摘要】：目的探讨老年突发性耳聋患者血清可溶性血管细胞黏附分子(s VCAM)-1水平及其影响因素。方法选择老年突发性耳聋患者50例作为突发性耳聋组,同期年龄匹配的老年无突发性耳聋者50例作为对照组。采用ELISA法测定血清s VCAM-1水平。结果老年突发性耳聋组血清s VCAM-1水平高于对照组(P0.05);老年突发性耳聋患者中男性患者和女性比较差异无统计学意义(P0.05),有并发症患者血清s VCAM-1水平高于无并发症患者(P0.05),有上呼吸道感染史患者高于无上呼吸道感染史患者(P0.05),生活习惯规律患者和生活习惯不规律患者、饮酒患者和不饮酒患者、吸烟患者和不吸烟患者及不同程度耳聋患者血清s VCAM-1水平比较差异无统计学意义(P0.05)。结论老年突发性耳聋患者血清s VCAM-1升高,其水平与合并心、脑血管并发症及上呼吸道感染有关。
[Abstract]:Objective to investigate the serum soluble vascular cell adhesion molecule (s VCAM)-1) and its influencing factors in elderly patients with sudden deafness. Methods 50 elderly patients with sudden deafness were selected as the sudden deafness group, and 50 aged patients without sudden deafness as the control group. Serum s VCAM-1 levels were measured by ELISA method. Results the level of serum s VCAM-1 in the elderly patients with sudden deafness was higher than that in the control group (P0.05). There was no significant difference between male and female in elderly patients with sudden deafness (P0.05). The serum s VCAM-1 level in patients with complications was higher than that in patients without complications (P0.05). Patients with history of upper respiratory tract infection were higher than those with no history of upper respiratory tract infection (P0.05), patients with regular living habits and irregular living habits, drinkers and non-drinkers, There was no significant difference in serum s VCAM-1 levels between smoking patients and non smoking patients and deafness patients with different degrees of deafness (P0.05). Conclusion the level of serum s VCAM-1 in elderly patients with sudden deafness is increased, which is related to the complication of heart, cerebrovascular disease and upper respiratory tract infection.
【作者单位】：台州市中心医院台州学院附属医院耳鼻喉科;
【分类号】：R764.437

【相似文献】