儿童变应性鼻炎伴哮喘患病率的Meta分析

发布时间：2019-02-12 21:28

【摘要】：目的:儿童变应性鼻炎和哮喘被认为具有相似的发病机制,但目前关于儿童变应性鼻炎伴哮喘患病率的大样本研究较少,因此该文借助循证医学的方法通过Meta分析了解儿童变应性鼻炎伴哮喘的患病率。方法:系统检索Pubmed、Science、Springer、Elsevier、Embase、BMJ Journals、万方数据库、维普数据库、中国生物医学文献数据库、相关期刊论文等数据库查找关于儿童变应性鼻炎伴哮喘患病率的文献,同时追索纳入文献的参考文献。采用R3.2.3软件对各研究结果进行分析。结果:共纳入15篇Cross-sec-tional studies。Meta分析结果显示,中国变应性鼻炎患儿中伴哮喘的患病率高达35.01%(95%CI 32.32%~37.70%),国外变应性鼻炎患儿中伴哮喘的患病率达31.59%(95%CI28.02%~35.16%)。结论:变应性鼻炎患儿伴哮喘的患病率高,中国变应性鼻炎患儿伴哮喘的患病率高于国外。
[Abstract]:Objective: children with allergic rhinitis and asthma are thought to have similar pathogenesis, but there are few studies on the prevalence of allergic rhinitis with asthma in children. Therefore, the prevalence of allergic rhinitis with asthma in children was analyzed by Meta. Methods: Pubmed,Science,Springer,Elsevier,Embase,BMJ Journals, Wanfang database, Weipu database and Chinese biomedical literature database were searched systematically. The Chinese Journal Full-text Database was used to search the literature on the prevalence of allergic rhinitis with asthma in children, and the references were also found. The research results were analyzed by software R3.2.3. Results: the results of 15 Cross-sec-tional studies.Meta analyses showed that the prevalence of asthma in Chinese children with allergic rhinitis was as high as 35.01% (95%CI 32.32 卤37.70%). The prevalence of asthma in children with allergic rhinitis abroad was 31.59% (95 CI 28.02 and 35.16%). Conclusion: the prevalence of allergic rhinitis with asthma in children with allergic rhinitis is higher than that in Chinese children with allergic rhinitis.
【作者单位】：重庆医科大学附属儿童医院耳鼻咽喉头颈外科;
【基金】：社会事业与民生保障科技创新专项(No:cstc2015shmszx120022)
【分类号】：R765.21;R725.6

【参考文献】