Angio-OCT与FD-OCT的眼底检查相关性分析

发布时间：2019-03-06 19:57

【摘要】：目的:比较两种光学相干断层成像术(optical coherence tomography,OCT):血流成像光学相干断层成像术(Angiooptical coherence tomography,Angio-OCT)和傅立叶域光学相干断层成像术(Fourier domain-optical coherence tomography,FD-OCT)眼底检查的相关性及差异性。方法:分别用Angio-OCT和FD-OCT测量20例受试者双眼神经纤维层厚度、视盘各参数和节细胞复合体厚度等,并对两种仪器测量值进行比较,采用Pearson相关分析研究两种仪器测量值的相关性,用配对样本t检验比较两种仪器测量值的差异性。结果:(1)两种OCT所测RNFL厚度、视盘参数及GCC厚度,总体相关性为0.7~0.8。(2)Angio-OCT所测GCC厚度比FD-OCT所测平均值高,但其它参数如RNFL厚度、视盘面积等,Angio-OCT的测量值普遍比FD-OCT的测量值低。结论:两种OCT的测量值(RNFL厚度、视盘参数、GCC厚度)有一定相关性,但不能直接比较。
[Abstract]:Objective: to compare two kinds of optical coherence tomography (optical coherence tomography,OCT): blood flow imaging optical coherence tomography (Angiooptical coherence tomography,Angio-OCT) and Fourier domain optical coherence tomography (Fourier domain-optical coherence tomography,). Correlation and difference of fundus examination in FD-OCT. Methods: Angio-OCT and FD-OCT were used to measure the thickness of nerve fiber layer, optic disc and ganglion cell complex in 20 subjects. The correlation between the measured values of the two instruments was studied by Pearson correlation analysis, and the difference of the measured values between the two instruments was compared by paired sample t-test. Results: (1) the total correlation of RNFL thickness, disc parameters and GCC thickness measured by two kinds of OCT was 0.7 脳 0.8. (2) the GCC thickness measured by Angio-OCT was higher than the average measured by FD-OCT, but other parameters such as RNFL thickness, disc area, etc. The measured value of Angio-OCT is generally lower than that of FD-OCT. Conclusion: the measured values of two kinds of OCT (RNFL thickness, optic disc parameter, GCC thickness) have certain correlation, but can not be compared directly.
【作者单位】：安徽医科大学解放军306医院临床学院;解放军306医院眼科;第三军医大学;
【基金】：国家自然科学基金资助项目(No.81271016)
【分类号】：R770.4

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