耳后注射联合口服激素治疗平坦下降型突发性聋的临床疗效分析

发布时间：2019-03-08 16:38

【摘要】：目的:分析耳后注射联合口服激素治疗平坦下降型突发性聋的临床疗效。方法:收集2015年以来收治的128例平坦下降型突发性聋患者的资料,随机分为耳后注射组(64例,注射用甲泼尼龙琥珀酸钠40mg加利多卡因2.5ml,耳后沟局部注射,隔日1次,联合晨起顿服甲泼尼龙片24mg,连服3d)和非耳后注射组(64例,晨起顿服甲泼尼龙片24mg,连服3d)。采用SPSS 17.0软件对2组患者的听力疗效进行统计分析。结果:(1)耳后注射组中15例(23.4%)治愈,9例(14.1%)显效,24例(37.5%)有效,16例(25.0%)无效,总有效率为75.0%(48/64);非耳后注射组中13例(20.3%)治愈,7例(10.9%)显效,21例(32.8%)有效,23例(35.9%)无效,总有效率为64.1%(41/64);2组患者疗效对比差异有统计学意义(P0.05);(2)耳后注射组250~8 000 Hz中的低、中、高频等5个不同频率段提高依次为(26.48±6.23)dBHL,(23.24±4.21)dBHL,(21.89±7.34)dBHL,(26.07±7.01)dBHL,(25.75±5.14)dBHL。耳后注射组250~500 Hz及250~4 000 Hz频率段听力改善明显高于非耳后注射组,差异有统计学意义(P0.05)。结论:耳后注射联合口服激素治疗平坦下降型突发性聋患者疗效较口服激素更佳。
[Abstract]:Objective: To analyze the clinical effect of post-ear injection combined with oral hormone in the treatment of flat-down sudden deafness. Methods: The data of 128 cases of flat-type sudden deafness in our hospital since 2015 were collected and divided into the following groups: the post-ear injection group (64 cases, the sodium methylprednisolone sodium succinate 40 mg for injection), the lidocaine 2.5ml, the local injection of the after-ear ditch, the other day, and the 24 mg of methylprednisolone tablets in the combined morning. (3 d) and non-ear post-injection (64 cases,24 mg of methylprednisolone tablets and 3d). The results of the statistical analysis of the hearing effect of the two groups were analyzed by SPSS 17.0 software. Results: (1) In the post-ear injection group,15 (23.4%) were cured,9 (14.1%) were effective,24 (37.5%) were effective,16 (25.0%) were not valid and the total effective rate was 75.0% (48/64); 13 (20.3%) were cured in the non-ear injection group,7 (10.9%) were effective,21 (32.8%) were effective,23 (35.9%) were not valid, the total effective rate was 64.1% (41/64), and the difference between the two groups was statistically significant (P0.05); (2) the low, medium, 5 different frequency segments, such as high-frequency, were (26.48-6.23) dBHL, (23.24-4.21) dBHL, (21.89-7.34) dBHL, (26.07-7.01) dBHL, (25.75-5.14) dBHL. The hearing improvement of 250-500 Hz and 250-4,000 Hz frequency band in the post-ear injection group was significantly higher than that of the non-post-ear injection group (P0.05). Conclusion: The effect of post-ear injection combined with oral hormone on the treatment of flat-down sudden deafness is better than that of oral hormone.
【作者单位】：新疆医科大学第二附属医院耳鼻咽喉科;
【分类号】：R764.437

【相似文献】