青少年孔源性视网膜脱离外路术后视网膜结构与视功能恢复的相关性分析

发布时间：2019-03-21 09:02

【摘要】：目的:应用多焦视网膜电流图(multifocal electroretinogram,mfERG)及光学相干断层扫描(optical coherence tomography,OCT)分析青少年孔源性视网膜脱离外路术前术后视网膜解剖结构的变化和功能恢复的关系。方法:收集2015年6月-2016年6月于我院就诊的孔源性视网膜脱离患者38例(39眼),其中男25例(26眼),女13例(13眼),年龄30岁,PVRC级。所有患者均由同一经验丰富的眼底医生行外路手术。术前以及术后1m,3m,6m行mfERG及OCT检查,分别记录1环及鼻、颞侧视网膜P1波平均振幅密度和黄斑中心凹及其鼻、颞侧ILM-RPE平均厚度,通过软件进行统计分析。结果:本组患者术前1d,术后1m,3m,6m mfERG 1环及鼻,颞侧视网膜P1波平均振幅密度:两侧观察区P1波平均振幅随时间持续升高,且鼻侧观察区平均振幅密度升高明显,差异有统计学意义(P0.05);1环术前1d至术后1m P1波平均振幅密度降低,之后随时间逐渐升高,差异有统计学意义(P0.05)。患者术前1d,术后1m,3m,6m OCT后极部视网膜ILM-RPE平均厚度持续降低,并维持在正常范围内,且黄斑颞侧观察区ILM-RPE平均厚度明显减少,差异有统计学意义(P0.05)。结论:1.青少年孔源性视网膜脱离选择外路手术对于视网膜解剖结构和功能的恢复有良好效果。2.OCT显示残余黄斑视网膜下积液是影响青少年孔源性视网膜脱离外路术后视网膜功能恢复的主要原因之一。3.mfERG是客观评价后极部各区域视网膜功能变化的重要手段。
[Abstract]:Objective: To study the relationship between the changes of the retinal anatomical structure and the function recovery after the pre-operation of the rhegmatogenous retinal detachment in the adolescent with multi-focal retinal current (mfrERG) and optical coherence tomography (OCT). Methods:38 cases (39 eyes) of the rhegmatogenous retinal detachment in our hospital from June 2015 to June 2016 were collected, of which 25 were male (26 eyes),13 (13 eyes),30 years old and PVRC. All patients were operated by the same experienced ophthalmologist. MfERG and OCT were performed before and after 1 m,3 m and 6 m, respectively. The mean amplitude density of the P1 wave and the mean thickness of the central and the nose and the lateral side of the retina were recorded in 1 ring and the nose, and the mean thickness of the lateral ILM-RPE was measured by the software. Results: The average amplitude density of P1-wave in the two-side observation region increased with the time, and the mean amplitude density of the nasal-side observation region was significantly higher than that of the two-side observation region (P0.05). The mean amplitude density of the 1-m-1 wave before and after 1-ring operation was decreased, and then the difference was statistically significant (P0.05). The mean thickness of the retinal ILM-RPE was decreased and the mean thickness of ILM-RPE in the observation area of the side of the macula was significantly reduced and the difference was statistically significant (P0.05). Conclusion:1. 2. OCT showed that residual macular subretinal effusion was one of the main causes of retinal function recovery after retinal detachment. The changes of retinal function in various regions of the department.
【学位授予单位】：南昌大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R779.6

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