急性脑梗死患者阻塞性睡眠呼吸暂停的体位研究
发布时间:2019-06-09 20:14
【摘要】:目的探究急性脑梗死患者阻塞性睡眠呼吸暂停(obstrustive sleep apnea-hypopnea syndrome,OSAHS)的体位特征,为合并OSAHS的脑梗死患者寻找体位干预的理论依据和临床干预方法。方法连续入选经头颅MRI检查证实并经多导睡眠图(PSG)检查诊断为急性脑梗死合并OSAHS的患者,根据PSG结果,将仰卧位AHI≥其它体位AHI2倍的患者定为体位性OSAHS(positional patientsPP),将仰卧位AHI其它体位AHI2倍的患者定为非体位性OSAHS(non-positional patients NPP)。比较体位性和非体位性OSAHS脑梗死患者的睡眠呼吸紊乱的体位特征、卒中危险因素、临床特征及头颅MRI的特征。比较合并OSAHS的脑梗死与非脑梗死患者睡眠呼吸紊乱的体位特征及危险因素。结果连续筛查的122脑梗死病例中,67.2%(82/122)合并睡眠呼吸紊乱,其中87.8%(72/82)患者为OSAHS,3.7%(3/82)为中枢性睡眠呼吸紊乱(CSA),8.5%(7/82)的为混合性睡眠呼吸紊乱(MSA)。脑梗死组高血压、糖尿病、血脂增高和吸烟患者均明显高于非脑梗死组P0.05。72例合并OSAHS的脑梗死者中体位性OSAHS为58.3%(42/72),其仰卧位AHI为30.70±11.20,仰卧位时间为55.6%,非体位性OSAHS为41.7%(30/72),,仰卧位AHI为19.66±8.9,仰卧位时间45.2%,P0.05。体位性脑梗死组高血压、高脂血症和心脏病患病率高于非体位组。首次脑梗死与复发脑梗死组比较显示,无论PP组还是NPP组复发组睡眠呼吸紊乱程度更重。不同部位梗死分析显示后循环梗死PP发生率为75%,前循环为51%,前后循环为63.6%,前后循环比较有显著性,P0.05。将脑梗死分为腔隙梗死组和非腔隙梗死组后发现后者PP发生率高(P=0.047),且更多地采取仰卧位睡眠(P=0.001)。NIHSS分值≥7组PP发生率为84.6%(11/13),AHI为32.12,仰卧位AHI为35.43,仰卧位时间72.3%,NIHSS7分组PP发生率为52.5%(31/59),AHI为26.04,仰卧位AHI为29.34,仰卧位时间63.5%(P=0.034)。结论急性脑梗死患者体位性OSAHS患病率高,卒中复发率高,梗死面积大,神经功能损伤重。早期积极筛查、评估和体位干预有可能改变合并体位性OSAHS脑梗死的转归。
[Abstract]:Objective to investigate the postural characteristics of obstructive sleep apnea (obstrustive sleep apnea-hypopnea syndrome,OSAHS) in patients with acute cerebral infarction (ACI), and to find the theoretical basis and clinical intervention method for postural intervention in patients with cerebral infarction complicated with OSAHS. Methods patients with acute cerebral infarction complicated with OSAHS confirmed by cephalic MRI and diagnosed by polysomnography (PSG) were enrolled in this study. According to the results of PSG, the patients with AHI 鈮
本文编号:2495867
[Abstract]:Objective to investigate the postural characteristics of obstructive sleep apnea (obstrustive sleep apnea-hypopnea syndrome,OSAHS) in patients with acute cerebral infarction (ACI), and to find the theoretical basis and clinical intervention method for postural intervention in patients with cerebral infarction complicated with OSAHS. Methods patients with acute cerebral infarction complicated with OSAHS confirmed by cephalic MRI and diagnosed by polysomnography (PSG) were enrolled in this study. According to the results of PSG, the patients with AHI 鈮
本文编号:2495867
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