改良睑板腺压榨法治疗睑板腺功能障碍效果观察

发布时间：2019-08-06 18:54

【摘要】：目的观察改良睑板腺压榨法治疗睑板腺功能障碍的效果。方法选择睑板腺功能障碍患者74例,其中32例(对照组)采用传统睑板腺压榨法治疗,42例(观察组)采用改良睑板腺压榨法治疗,随访2个月。治疗前后,行眼表面疾病指数(OSDI)、睑板腺积分评价及泪液分泌试验(SIT),采用滤纸条检查泪膜破碎时间(BUT),结膜荧光素钠染色检查(FL)评价结膜病变;采用印迹细胞法于压榨处的下眼睑结膜面取材,PAS染色后观察压榨处结膜损伤情况;记录手术时间及患者术后不适感。结果两组治疗后,BUT、SIT较治疗前提高,OSDI、睑板腺积分及FL下降,差异有统计学意义(P均0.05);治疗后,观察组BUT、SIT高于对照组,OSDI、睑板腺积分及FL低于对照组,差异有统计学意义(P均0.05)。观察组睑结膜上皮损伤1级30例、2级12例,对照组睑结膜上皮损伤3级13例、4级19例,两组比较差异有统计学意义(P0.01)。观察组手术时间(2.6±0.7)min,短于对照组的(14.9±3.3)min(P0.01)。观察组20例诉有眼部刺激感,其中9例为明显刺激感、11例为轻度刺激感;对照组32例术后均诉眼部有刺激感,其中25例主诉有明显刺激感、7例诉有轻度刺激感;两组术后不适情况比较,差异有统计学意义(P0.05)。结论改良睑板腺压榨法治疗睑板腺功能障碍临床疗效好、损伤小。
[Abstract]:Objective to observe the effect of modified tarsal gland pressing on tarsal gland dysfunction. Methods 74 patients with tarsal gland dysfunction were selected. 32 patients (control group) were treated with traditional tarsal gland pressing method and 42 patients (observation group) were treated with modified tarsal gland pressing method. The patients were followed up for 2 months. Before and after treatment, the eye surface disease index (OSDI),) tarsal gland score and tear secretion test (SIT), were used to evaluate the conjunctival lesions by filter paper strip, (BUT), conjunctival fluorescein sodium staining was used to evaluate conjunctival lesions, and imprinted cell method was used to take materials from the conjunctival surface of the lower eyelid at the pressing site, and the conjunctival injury at the pressing site was observed after PAS staining. The operation time and postoperative discomfort of the patients were recorded. Results after treatment, BUT,SIT increased, OSDI, tarsal gland score and FL decreased significantly in the two groups, BUT,SIT in the observation group was higher than that in the control group, OSDI, tarsal gland score and FL were significantly lower than those in the control group (P < 0.05). There were 30 cases of grade 1 conjunctival epithelial injury and 12 cases of grade 2 eyelid conjunctival epithelial injury in the observation group, and 13 cases in the control group were grade 3 and 19 cases in grade 4. There was significant difference between the two groups (P 0.01). The operation time of the observation group (2.6 卤0.7) min, was shorter than that of the control group (14.9 卤3.3) min (P 0.01). In the observation group, 20 cases complained of ocular irritation, including 9 cases of obvious irritation and 11 cases of mild irritation, while 32 cases of the control group complained of irritation of the eye after operation, of which 25 cases complained of obvious irritation and 7 cases complained of mild irritation. There was significant difference between the two groups (P 0.05). Conclusion the modified tarsal gland pressing method is effective in the treatment of tarsal gland dysfunction.
【作者单位】：河北省人民医院;
【基金】：河北省卫生和计划生育委员会基金资助项目(20150136)
【分类号】：R779.6

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