营养对重症急性胰腺炎患者肠源性感染的影响研究

发布时间：2018-01-29 22:10

本文关键词： 肠内营养肠外营养重症急性胰腺炎肠源性感染临床影响程度白细胞 C-反应蛋白　出处：《中华医院感染学杂志》2016年02期 　论文类型：期刊论文

【摘要】：目的探究肠内营养(EN)与肠外营养(PN)对重症急性胰腺炎肠源性感染的临床影响程度,为临床治疗提供数据参考。方法选取2014年1月-2015年8月110例重症急性胰腺炎肠源性感染患者,按照不同的营养方式将患者分为试验组与对照组各55例;两组患者均给予常规治疗,观察组给予EN治疗,对照组给予PN治疗,对比分析两组患者肠源性感染指标的变化,采用SPSS12.0软件进行统计数据分析。结果患者治愈率观察组为94.55%、对照组为85.45%,两组比较差异有统计学意义(P0.05);不良反应发生率观察组为12.73%、对照组为40.00%,两组比较差异有统计学意义(P0.05);EN与PN在血白细胞、内毒素以及C-反应蛋白等方面的临床指标比较差异有统计学意义(P0.05)。结论重症急性胰腺炎肠源性感染患者早期实施EN的治疗方式,治疗效果最理想;EN治疗方式可有效提高治愈率,降低不良反应发生率,从而减轻重症急性胰腺炎肠源性感染患者的痛苦,值得临床推广。
[Abstract]:Objective to investigate the clinical effect of enteral nutrition (en) and parenteral nutrition (PN) on enterogenous infection in severe acute pancreatitis (SAP). Methods from January 2014 to August 2015, 110 patients with enterogenous infection of severe acute pancreatitis were selected. According to different nutrition methods, the patients were divided into experimental group and control group, 55 cases in each group. Two groups of patients were given routine treatment, the observation group was given en treatment, the control group was given PN treatment, the two groups were compared and analyzed the change of enterogenous infection index. Results the cure rate was 94.55 in the observation group and 85.45 in the control group. The difference between the two groups was statistically significant (P 0.05). The incidence of adverse reactions in observation group was 12.73 and in control group was 40.00.The difference between the two groups was statistically significant (P 0.05). En and PN were found in white blood cells. There were significant differences in the clinical indexes of endotoxin and C-reactive protein. Conclusion the treatment of en in the patients with enterogenous infection in severe acute pancreatitis is early. The therapeutic effect is the most ideal. En treatment can effectively improve the cure rate and reduce the incidence of adverse reactions, thus alleviating the pain of severe acute pancreatitis patients with enterogenic infection, and it is worthy of clinical promotion.
【作者单位】：青海红十字医院ICU;
【基金】：青海省卫生计生指导性基金资助项目(2014KRB029)
【分类号】：R576
【正文快照】： 重症急性胰腺炎的病死率非常高,根据相关文献资料报道显示,全球有85.50%以上的重症急性胰腺炎患者均发生了肠源性感染。因此,相关炎症及感染问题已引起高度关注,如何解决重症急性胰腺炎的相关感染问题已是迫在眉睫。本研究探讨肠内营养(EN)与肠外营养(PN)对重症急性胰腺炎肠源

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