垂直律动治疗老年功能性便秘患者的临床疗效

发布时间：2018-03-26 09:02

本文选题：老年人　切入点：功能性便秘　出处：《上海医学》2017年03期

【摘要】：目的评价垂直律动治疗老年功能性便秘患者的临床疗效及其安全性。方法选取68例老年功能性便秘患者,随机分入对照组(维持继往药物治疗)和垂直律动组(在维持继往药物治疗的基础上进行全身重直律动训练),疗程均为6周。分别于治疗前和疗程结束后1周内记录患者的排便情况,包括大便性状(Bristol评分)、每周排便次数、排便时间和便秘患者的生活质量评估(PAC-QOL)量表评分,并测定血常规、肝功能[天冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)、白蛋白]、肾功能(肌酐、尿酸)、血电解质(钠离子、钾离子)指标。观察并记录治疗期间不良反应(包括腹痛、腹胀、腹泻、呕吐等)发生情况。结果垂直律动组治疗后的每周排便次数显著多于同组治疗前(P0.05),排便时间显著短于同组治疗前(P0.05),Bristol评分显著高于同组治疗前(P0.05),PAC--QOI,量表评分显著低于同组治疗前(P0.05);对照组治疗后的排便时间显著短于同组治疗前(P0.05),PAC-QOL量表评分显著低于同组治疗前(P0.05)。垂直律动组治疗后的每周排便次数显著多于对照组治疗后(P0.05),排便时间显著短于对照组治疗后(P0.05),Bristol评分显著高于对照组治疗后(P0.05),PAC-QOL量表评分显著低于对照组治疗后(P0.05)。两组内治疗前后红细胞计数、白细胞计数,以及AST、ALT、白蛋白、尿酸、肌酐、钠离子、钾离子水平的差异均无统计学意义(P值均0.05);两组间治疗前和治疗后上述各项指标的差异亦均无统计学意义(P值均0.05)。治疗期间两组均无1例患者发生腹痛、腹胀、腹泻、呕吐等不良反应。结论垂直律动治疗能改善老年功能性便秘患者的症状,提高其生活质量。
[Abstract]:Objective to evaluate the clinical efficacy and safety of perpendicular rhythm in the treatment of senile functional constipation. They were randomly divided into two groups: control group (maintenance followed by drug therapy) and vertical rhythmic group (after maintenance of drug therapy). The course of treatment was 6 weeks. The course of treatment was 6 weeks before and 1 week after the end of the course of treatment, respectively. Record the patient's defecation, These include stool trait Bristol score, weekly defecation times, defecation time and quality of life assessment of constipation patients (PAC-QOLscale), blood routine, liver function [aspartate transaminase (AST), alanine aminotransferase (alt), albumin], renal function (creatinine, creatinine), and renal function (creatinine). Uric acid, blood electrolytes (sodium, potassium). Adverse reactions (including abdominal pain, abdominal distension, diarrhea) during treatment were observed and recorded. Results the frequency of defecation per week in the perpendicular rhythmic group was significantly higher than that in the same group before treatment, and the defecation time was significantly shorter than that in the same group before treatment. The score of Bristol was significantly higher than that in the same group before treatment, and the score of the scale was significantly lower than that of the same group before treatment. The defecation time after treatment in the control group was significantly shorter than that in the control group before treatment, and the score of PAC-QOL in the control group was significantly lower than that in the same group before treatment. The times of defecation per week in the perpendicular rhythm group were significantly higher than those in the control group after treatment, and the defecation time in the perpendicular rhythm group was significantly higher than that in the control group after treatment. The score of Bristol after treatment in control group was significantly lower than that in control group after treatment, and the score of PAC-QOL was significantly lower than that in control group before and after treatment, and the erythrocyte count before and after treatment in both groups was significantly lower than that in control group. White blood cell count, as well as alt, albumin, uric acid, creatinine, sodium ions, There was no significant difference in potassium level between the two groups before and after treatment, and there was no significant difference in P value between the two groups before and after treatment. During the treatment period, there was no abdominal pain, abdominal distension, diarrhea in both groups, and there was no significant difference between the two groups in abdominal pain, abdominal distension and diarrhea. Conclusion Vertical rhythm therapy can improve the symptoms and quality of life of senile patients with functional constipation.
【作者单位】：复旦大学附属华东医院康复医学科;复旦大学附属华东医院推拿科;复旦大学附属华东医院消化科;上海中医药大学护理学院;
【基金】：上海市科学技术委员会课题(15411965200) 上海市卫生和计划生育委员会中医药科研专项(2016LP021)资助项目
【分类号】：R574.62

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