不同ABO血型炎症性肠病患者幽门螺杆菌感染状况研究

发布时间：2018-04-11 04:22

本文选题：炎症性肠病 + ABO血型　；参考：《广东医学》2017年17期

【摘要】：目的探讨不同ABO血型的炎症性肠病(IBD)患者与幽门螺杆菌(Hp)感染的关系。方法经临床、内镜及病理确诊的IBD患者151例为IBD组,同时收集151例年龄、性别匹配的健康体检者为对照组,采用微柱法检测ABO血型,通过血Hp抗体和~(13)C/~(14)C尿素呼气试验检测Hp感染情况,比较两组ABO血型与Hp感染的相关性。结果克罗恩病(CD)患者59例,溃疡性结肠炎(UC)患者92例。IBD组与对照组的血型分布比较差异无统计学意义(P0.05);CD组和UC组Hp感染率均低于对照组,差异均有统计学意义(P0.05);O型和B型血IBD患者的Hp感染率均低于对照组(15.9%vs 25.2%,7.3%vs 14.6%),差异有统计学意义(P0.05)。结论IBD患者的血型分布与正常人群无明显差异,但O型和B型血IBD患者的Hp感染率较正常人群更低。
[Abstract]:Objective to investigate the relationship between infection of Helicobacter pylori (HP) and inflammatory bowel disease (IBD) with different ABO blood groups.Methods 151 patients with IBD confirmed by clinical, endoscopic and pathological examination were selected as IBD group, and 151 healthy persons with age and sex matched as control group. ABO blood group was detected by microcolumn method.HP infection was detected by blood HP antibody and urea breath test (urea breath test). The correlation between HP infection and ABO blood group was compared between the two groups.Results there were 59 patients with Crohn's disease and 92 patients with ulcerative colitis. There was no significant difference in blood group distribution between IBD group and control group. HP infection rate in CD group and UC group was lower than that in control group.The HP infection rate in patients with IBD of P0.05O and B was lower than that of the control group (15.9 vs 25.2and 7.3vs 14.6C), and the difference was statistically significant (P 0.05).Conclusion there was no significant difference in blood group distribution between IBD patients and normal subjects, but HP infection rate in IBD patients with O and B blood was lower than that in normal controls.
【作者单位】：南方医科大学附属南海医院消化内科;南方医科大学附属南海医院肾内科;
【基金】：佛山市医学类科技攻关项目(编号:2015AB000012)
【分类号】：R574

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