生大黄肠道透析联合非生物型人工肝治疗急性肝衰竭临床疗效分析

发布时间：2018-04-29 04:03

本文选题：生大黄 + 肠道透析　；参考：《时珍国医国药》2015年06期

【摘要】：目的探讨生大黄肠道透析联合非生物型人工肝血浆置换(PE)治疗急性肝衰竭的临床疗效。方法采用生大黄取汁200ml行灌肠,联合非生物型人工肝PE治疗急性肝衰竭100例,并与单纯非生物型人工肝PE治疗急性肝衰竭100例对照以比较其疗效。结果生大黄肠道透析联合PE治疗急性肝衰竭总有效率为89.0%,单纯PE治疗总疗效率71.0%,两组比较有明显统计学意义(P0.05)。生大黄肠道透析联合PE治疗组血氨明显下降,与单纯PE治疗组相比有显著统计学意义(P0.05)。生大黄肠道透析联合PE治疗组肝功能改善率83例(83.0%),单纯PE治疗组肝功能改善率61例(61.0%),两组比较差异有明显统计学意义(P0.05)。生大黄肠道透析联合PE治疗组凝血功能明显改善,两组比较具有统计学意义(P0.05)。并发症发生率生大黄肠道透析联合PE治疗组55例(55.0%),单纯PE治疗组75例(75.0%),两组比较具有统计学意义(P0.05)。结论生大黄肠道透析联合非生物型人工肝治疗急性肝衰竭具有良好的疗效,值得临床推广。
[Abstract]:Objective to investigate the clinical effect of rhubarb intestinal dialysis combined with non-biological artificial liver plasma exchange (PEV) in the treatment of acute liver failure. Methods 100 cases of acute liver failure were treated with rhubarb juice and 200ml, and 100 cases of acute hepatic failure were treated with non-biological artificial liver PE, and compared with 100 cases of acute liver failure treated with pure non-biological type of artificial liver PE. Results the total effective rate of rhubarb intestinal dialysis combined with PE in treatment of acute liver failure was 89.0, and the total curative effect rate of pure PE was 71.0. There was significant difference between the two groups (P 0.05). The blood ammonia in the rhubarb group treated with intestinal dialysis combined with PE was significantly lower than that in the pure PE group (P 0.05). The improvement rate of liver function was 83.0 in the rhubarb intestinal dialysis group and 61.0 in the pure PE group. The difference between the two groups was statistically significant (P 0.05). The coagulation function of rhubarb intestinal dialysis combined with PE treatment group was significantly improved, and the two groups had statistical significance (P 0.05). The incidence of complications was 55 cases in the rhubarb intestinal dialysis combined with PE treatment group and 75 cases in the pure PE treatment group. There was significant difference between the two groups (P 0.05). Conclusion Radix et Rhizoma et Rhizoma rhubarb enteral dialysis combined with abiotic artificial liver is effective in the treatment of acute liver failure and is worth popularizing.
【作者单位】：大理学院附属昆明市第三人民医院;
【基金】：云南省昆明市科技局科技社会发展重大项目(No.2013-01-00-B-S-02-0001)
【分类号】：R575.3

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