社区综合干预对慢性便秘疗效影响的Meta分析

发布时间：2018-06-20 17:58

本文选题：便秘 + 社区干预　；参考：《中国全科医学》2017年21期

【摘要】：目的通过Meta分析方法探讨社区综合干预对慢性便秘疗效的影响。方法检索国内主要医学数据库,包括中国生物医学文献数据库(CBM)(1978—2017年)、维普网(VIP)(1989—2017年)、中国知网(CNKI)(1979—2017年)、万方数据知识服务平台(1990—2017年),Pub Med/Medline(1966—2017年)。筛选采用社区综合性干预为干预方法的随机对照试验。提取文献相关信息,并评价纳入文献质量。结果纳入6篇文献,其中干预组587例,对照组575例。Meta分析结果显示,干预组治疗有效率高于对照组[相对危险度(RR)=1.50,95%CI(1.18,1.92),P0.001]。治疗3个月时,干预组每周排便次数高于对照组、大便性状评分低于对照组、排便困难程度评分低于对照组[加权均数差(WMD)=0.30,95%CI(0.21,0.39),P0.001;WMD=-1.51,95%CI(-2.09,-0.92),P0.001;WMD=-0.57,95%CI(-0.67,-0.48),P0.001]。治疗6个月时,干预组每周排便次数高于对照组、大便性状评分低于对照组、排便困难程度评分低于对照组[WMD=1.65,95%CI(1.55,1.75),P0.001;WMD=-0.69,95%CI(-0.96,-0.41),P0.001;WMD=-0.92,95%CI(-1.31,-0.52),P0.001]。结论社区综合干预对慢性便秘的疗效优于单纯泄剂治疗。
[Abstract]:Objective to explore the effect of community comprehensive intervention on chronic constipation by meta-analysis. Methods the main medical databases in China, including China Biomedical Literature Database (CBM), Biomedical Literature Database (CBM), Biomedical Literature Database (CBM), Biomedical Literature Database (CBM), Biomedical Literature Database (CBM), China Biomedical Literature Database (CBM), China Biomedical Literature Database (CBM), China Biomedical Literature Database (CBM), China Biomedical Literature Database (CBM), China Biomedical Literature Database (CBM), China Biomedical Literature Database (CBM), China Biomedical Literature Database (CBM), VIPP (1989-2017), CNKI (1979-2017), and Wanfang data Service platform (1990-2017) were searched. A randomized controlled trial using community comprehensive intervention as intervention method was selected. Extract the relevant information and evaluate the quality of the literature. Results six articles were included, including 587 cases in the intervention group and 575 cases in the control group. The results of meta-analysis showed that the effective rate of the treatment in the intervention group was higher than that in the control group [RRRX 1.5095%]. After 3 months of treatment, the defecation frequency of intervention group was higher than that of control group, the score of defecation character was lower than that of control group, and the score of defecation difficulty was lower than that of control group. After 6 months of treatment, the defecation frequency of intervention group was higher than that of control group, the score of defecation character was lower than that of control group, and the score of defecation difficulty was lower than that of control group. Conclusion the effect of community comprehensive intervention on chronic constipation is better than that of catharsis alone.
【作者单位】：同济大学附属杨浦医院全科医学科;同济大学附属杨浦医院临床心理科;同济大学医学院全科医学系;
【基金】：上海市卫生和计划生育委员会科研课题(201440344) 上海市卫生计生系统重要薄弱学科建设计划(2015ZB0603)
【分类号】：R574.62

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