置管引流应用于重症急性胰腺炎继发腹腔感染的临床研究

发布时间：2018-07-17 06:49

【摘要】：目的探讨经皮穿刺置管引流应用于重症急性胰腺炎继发腹腔感染的临床疗效性和安全性。方法对2010年6月-2013年9月确诊为重症急性胰腺炎合并继发腹腔感染患者76例,随机分为观察组和对照组,各38例,对照组给予常规保守治疗,观察组给予影像引导下的经皮穿刺置管引流,观察两组患者临床疗效性和术后恢复等。结果治疗前,两组患者血白细胞及血、尿淀粉酶差异无统计学意义,治疗后,均明显改善,较治疗前差异有统计学意义(P0.05);治疗后,两组血白细胞差异无统计学意义,而血、尿淀粉酶差异有统计学意义(P0.05);观察组总有效率为92.1%、病死率为5.3%,对照组总有效率为78.9%、病死率为15.8%,差异均有统计学意义(P0.05);观察组患者症状体征消失的时间、住院天数及饮食恢复时间均短于对照组,差异均有统计学意义(P0.05)。结论影像引导下经皮穿刺置管引流是治疗重症急性胰腺炎继发腹腔感染安全可行的方法,能够通过微创的手术方法达到全面探查和充分引流的治疗目的,有效提高患者临床疗效,值得临床推广应用。
[Abstract]:Objective to investigate the clinical efficacy and safety of percutaneous catheter drainage for abdominal infection secondary to severe acute pancreatitis. Methods from June 2010 to September 2013, 76 patients with severe acute pancreatitis complicated with secondary abdominal infection were randomly divided into observation group (n = 38) and control group (n = 38). The patients in the observation group were treated with percutaneous puncture and drainage under the guidance of image. The clinical curative effect and postoperative recovery were observed in the two groups. Results before treatment, there was no significant difference in blood leukocyte, blood and urine amylase between the two groups. After treatment, the difference was significantly improved (P0.05), but the difference between the two groups was not statistically significant after treatment, but there was no significant difference between the two groups after treatment. The difference of urine amylase was statistically significant (P0.05), the total effective rate of observation group was 92.1, the mortality rate was 5.3, the total effective rate of control group was 78.9 and the mortality rate was 15.8.The difference was statistically significant (P0.05); the time of disappearance of symptoms and signs in observation group was significant (P0.05). Days of hospitalization and diet recovery time were shorter than the control group, the differences were statistically significant (P0.05). Conclusion Image guided percutaneous catheterization and drainage is a safe and feasible method for the treatment of abdominal infection secondary to severe acute pancreatitis. It is worth popularizing and applying to improve the clinical effect of patients.
【作者单位】：重庆三峡中心医院消化科;
【基金】：重庆市科技局基金资助项目(Nb2012-2-6-1)
【分类号】：R576

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