新疆维吾尔族人群与NAFLD的相关危险因素分析

发布时间：2018-09-18 15:29

【摘要】：目的探讨新疆地区维吾尔族人群非酒精性脂肪性肝病(NAFLD)的相关危险因素。方法收集新疆医科大学第一附属医院新入院维吾尔族患者及新疆医科大学体检中心维吾尔族健康体检者共966例,进行问卷调查及血生化和B超检查,依据体检情况分为NAFLD组(569例)和非NAFLD组(397例);按照体质量指数(BMI)和腰围身高比值(WHtR)分层对NAFLD组进行危险因素的相关性分析。结果两组对象BMI、WHtR比较,差异有统计学意义(P0.05);超重(OR=2.527,P0.05)和肥胖(OR=1.938,P0.05)是NAFLD的危险因素。多因素Logistic回归分析显示:BMI、空腹血糖(FPG)和三酰甘油(TG)与NAFLD有关(P0.05),是NAFLD的危险因素。结论BMI、WHtR、FPG和TG是NAFLD的危险因素,在评价和预测NAFLD的高危人群中具有一定的临床意义。
[Abstract]:Objective to investigate the risk factors of (NAFLD) in Uygur population in Xinjiang. Methods A total of 966 newly admitted Uygur patients in the first affiliated Hospital of Xinjiang Medical University and Uygur people in the Medical examination Center of Xinjiang Medical University were investigated by questionnaire and blood biochemistry and B-ultrasound examination. According to the physical examination, the patients were divided into NAFLD group (569 cases) and non-NAFLD group (397 cases), and the risk factors of NAFLD group were analyzed according to body mass index (BMI) and waist height ratio (WHtR) stratification. Results there was significant difference in BMI,WHtR between the two groups (P0.05), and overweight (OR=2.527,P0.05) and obesity (OR=1.938,P0.05) were the risk factors of NAFLD. Multivariate Logistic regression analysis showed that fasting blood glucose (FPG) and triglyceride (TG) were associated with NAFLD (P0.05), which were the risk factors of NAFLD. Conclusion BMI,WHtR,FPG and TG are risk factors for NAFLD, which has clinical significance in evaluating and predicting high risk population of NAFLD.
【作者单位】：新疆医科大学公共卫生学院劳动与环境卫生教研室;新疆维吾尔自治区妇幼保健医院检验科;新疆医科大学护理学院;
【基金】：国家自然科学基金资助项目(81460120)
【分类号】：R575

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