急性胆囊炎患者医院感染的病原菌分布与危险因素分析

发布时间：2018-10-21 14:52

【摘要】：目的分析急性胆囊炎患者发生医院感染的病原菌分布及危险因素,为急性胆囊炎患者医院感染的预防控制提供参考依据。方法选取2014年1月-2016年6月医院收治的410例急性胆囊炎患者为研究对象,统计医院感染率及病原菌分布,比较不同性别、年龄、基础疾病、介入性治疗及胆囊结石患者的医院感染率,采用logistic回归分析上述因素与急性胆囊炎患者医院感染的关系。结果 410例急性胆囊炎患者医院感染23例,医院感染率为5.61%,23例感染患者的送检标本中共分离出病原菌31株,其中革兰阴性菌21株占67.74%,革兰阳性菌8株占25.81%,真菌2株占6.45%,单因素分析结果显示,性别、年龄、基础疾病、介入性治疗及胆囊结石与急性胆囊炎患者医院感染的发生具有相关性(P0.05);多因素logistic回归分析结果显示,性别、年龄、基础疾病、介入性治疗及胆囊结石是急性胆囊炎患者发生医院感染的独立危险因素。结论革兰阴性菌是急性胆囊炎患者医院感染的主要病原菌,且性别、年龄、基础疾病、介入性治疗及胆囊结石情况均是导致医院感染的危险因素,临床应根据上述情况进行针对性干预。
[Abstract]:Objective to analyze the distribution and risk factors of nosocomial infection in patients with acute cholecystitis and to provide reference for the prevention and control of nosocomial infection in patients with acute cholecystitis. Methods 410 patients with acute cholecystitis treated in our hospital from January 2014 to June 2016 were selected as study subjects. The nosocomial infection rate and the distribution of pathogenic bacteria were analyzed, and the sex, age and underlying diseases were compared. Interventional therapy and nosocomial infection rate in patients with cholecystolithiasis were analyzed by logistic regression analysis and the relationship between these factors and nosocomial infection in patients with acute cholecystitis. Results among 410 patients with acute cholecystitis, 23 cases were nosocomial infection. The nosocomial infection rate was 5.61%. 31 strains of pathogenic bacteria were isolated from the specimens of 23 cases of acute cholecystitis. Among them, 21 strains of Gram-negative bacteria accounted for 67.74%, 8 strains of Gram-positive bacteria accounted for 25.81% and 2 strains of fungi accounted for 6.45%. The results of univariate analysis showed that sex, age, underlying diseases, Interventional therapy and gallstone were associated with nosocomial infection in patients with acute cholecystitis (P0.05). Multivariate logistic regression analysis showed that sex, age, underlying diseases, Interventional therapy and gallstone are independent risk factors for nosocomial infection in patients with acute cholecystitis. Conclusion Gram-negative bacteria are the main pathogens of nosocomial infection in patients with acute cholecystitis. Sex, age, basic diseases, interventional therapy and gallstone condition are the risk factors for nosocomial infection. Clinical intervention should be carried out according to the above situation.
【作者单位】：南阳市中心医院急诊科;
【分类号】：R575.61

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