梗阻性黄疸患者经皮经肝胆道引流术后胆道感染相关因素研究

发布时间：2019-04-20 12:33

【摘要】：目的研究梗阻性黄疸患者经皮经肝胆道引流术(PTCD)术后发生胆道感染的相关因素。方法选取2014年10月-2016年10月在医院接受治疗的120例梗阻性黄疸患者为研究对象,采用PTCD治疗,观察比较并分析患者术后发生胆道感染的相关因素。结果 120例梗阻性黄疸患者术后发生胆道感染22例,感染率18.33%;对120例梗阻性黄疸患者基本资料进行研究,结果显示年龄、术前黄疸天数、术前卡氏评分(KPS)、引流量、术前谷丙转氨酶(ALT)、碱性磷酸酶(ALP)、总胆红素(TBIL)等生化指标与术后出现胆道感染密切相关,差异有统计学意义(P0.05);其中术前黄疸天数过长、术前ALP指标水平过高是造成术后胆道感染的危险因素,术后引流良好是术后胆道感染的保护因素;性别、梗阻部位及引流方法均不影响术后胆道感染的发生,差异无统计学意义。结论梗阻性黄疸患者术后胆道感染的相关因素包括年龄、术前黄疸天数、术前KPS评分、引流量、术前ALT、ALP、TBIL等,其中造成术后胆道感染的危险因素主要包括术前黄疸天数过长、术前ALP指标水平过高,有效的引流能够促进手术的顺利实施,继而降低术后胆道感染发生率,属于术后胆道感染的保护因素。
[Abstract]:Objective to study the related factors of biliary tract infection after percutaneous transhepatic biliary drainage (PTCD) in patients with obstructive jaundice. Methods 120 patients with obstructive jaundice who were treated in hospital from October 2014 to October 2016 were selected and treated with PTCD. The related factors of postoperative biliary tract infection were compared and analyzed. Results there were 22 cases of biliary tract infection after operation in 120 cases of obstructive jaundice, the infection rate was 18.33%. The basic data of 120 patients with obstructive jaundice were studied. The results showed that age, days of preoperative jaundice, preoperative (KPS), drainage, preoperative glutamic pyruvic transaminase (ALT), alkaline phosphatase (ALP),. Total bilirubin (TBIL) and other biochemical indicators were closely related to postoperative biliary tract infection, the difference was statistically significant (P0.05); The long days of preoperative jaundice and the high level of preoperative ALP were the risk factors of postoperative biliary tract infection, and the good drainage after operation was the protective factor of postoperative biliary tract infection. Sex, site of obstruction and drainage method did not affect the occurrence of postoperative biliary tract infection, and there was no significant difference between the two groups. Conclusion the related factors of postoperative biliary tract infection in patients with obstructive jaundice include age, days of preoperative jaundice, preoperative KPS score, drainage volume, preoperative ALT,ALP,TBIL, and so on. The risk factors of postoperative biliary tract infection include long days of preoperative jaundice and high level of preoperative ALP. Effective drainage can promote the smooth implementation of the operation and then reduce the incidence of postoperative biliary tract infection, and the risk factors for postoperative biliary tract infection include long days before operation and high level of postoperative biliary tract infection. It belongs to the protective factor of postoperative biliary tract infection.
【作者单位】：宁波市第二医院肝胆胰科;
【分类号】：R575

【相似文献】