增龄对胃中间横带和胃内食物分布的影响

发布时间：2019-07-02 14:06

【摘要】：目的观察年龄对胃排空、胃中间横带(MTB)和胃内食物分布的影响。方法 50例健康志愿者按年龄不同分为青年组、中年组和老年组,进食99mTc-DTPA标记的试餐后利用双探头SPECT采集图像,通过计算机产生的像素将胃的每帧影像划分为近端胃、MTB、远端胃,分别测定、计算半排空时间、90 min胃内残留率、不同时相胃各部分面积、计数/像素比等。结果老年组近端胃半排空时间较青年组、中年组缩短(P0.05),远端胃90 min胃内核素残留率较青年组、中年组增多(均P0.05);老年组近端胃60、90 min时相面积较青年组、中年组明显减少(P0.05)。30、60、90 min时相老年组远端胃面积较青年组、中年组明显增加(均P0.05);在30、60、90 min时相老年组远端胃计数/像素比较青年组、中年组增加(P0.05)。老年组0、30、60、90 min MTB面积较青年组、中年组增宽(P0.05)。结论胃排空并不随着年龄的增加而改变,但老年人进食后存在胃内食物分布异常,可能与MTB增宽有关。
[Abstract]:Objective to observe the effect of age on gastric emptying, gastric transverse band (MTB) and gastric food distribution. Methods according to the age of 50 healthy volunteers, 50 healthy volunteers were divided into youth group, middle-aged group and elderly group according to their age. After eating 99mTc-DTPA marked test meal, the images were collected by double-probe SPECT. The images of each frame of stomach were divided into proximal stomach and MTB, distal stomach by computer. The half emptying time, 90 min gastric residual rate, the area of different parts of stomach, count / pixel ratio and so on were measured. Results the time of proximal gastric emptying in the elderly group was shorter than that in the young group (P 0.05), the residual rate of nuclide in the distal stomach 90 min in the distal stomach was higher than that in the young group, and the 90 min phase area in the elderly group was significantly lower than that in the young group (P 0.05). 30, 60, 90 min in the elderly group was significantly higher than that in the young group, and the area of the distal stomach in the middle age group was significantly higher than that in the middle age group (P 0.05). At 30, 60, 90 min, the distal stomach count / pixel in the elderly group was higher than that in the young group, and that in the middle-aged group was higher than that in the young group (P 0.05). The area of 90 min MTB in the elderly group was wider than that in the young group and middle-aged group (P 0.05). Conclusion gastric emptying does not change with the increase of age, but the abnormal distribution of gastric food in the elderly after eating may be related to the widening of MTB.
【作者单位】：兰州大学第一医院老年科;兰州大学第一医院核医学科;兰州大学第一医院消化科;甘肃中医药大学附属医院超声科;
【基金】：甘肃省自然基金资助项目(1308RJZA219) 甘肃省胃肠病重点实验室开放课题基金资助(gswcky-2012-004)
【分类号】：R573

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