不同抗菌药物治疗肝硬化上消化道出血感染患者的有效性与安全性评价

发布时间：2019-08-24 07:35

【摘要】：目的研究不同的抗菌药物治疗肝硬化上消化道出血并感染患者临床疗效以及安全性,为临床治疗提供参考依据。方法选择2010年5月-2013年3月接受治疗的126例肝硬化并发上消化道出血并感染患者为研究对象,将其随机分为A、B、C 3组,每组各42例,A组给予亚胺培南治疗、B组给予头孢他啶治疗、C组给予硫酸依替米星治疗,均以静脉滴注方式给药,比较3组患者疗效率,数据采用SPSS 16.0软件进行统计分析。结果 A、B、C 3组患者的治疗有效率分别为83.3%、85.7%、95.2%,A、B两组患者的治疗有效率比较,差异无统计学意义,A与C、B与C组的治疗有效率比较差异有统计学意义(P0.05)。结论硫酸依替米星是一种在治疗肝硬化并感染患者中优先选择的抗菌药物。
[Abstract]:Objective to study the clinical efficacy and safety of different antibiotics in the treatment of upper gastrointestinal bleeding complicated with liver cirrhosis, and to provide reference for clinical treatment. Methods from May 2010 to March 2013, 126 patients with liver cirrhosis complicated with upper gastrointestinal bleeding were randomly divided into three groups: group A (n = 42), group B (n = 42), group C (n = 42) and group C (n = 42). The data were statistically analyzed by SPSS 16.0 software. Results the effective rates of group A, group B and group C were 83. 3%, 85.7% and 95.2%, respectively. There was no significant difference between group B and group B. there was no significant difference in the effective rate between group B and group C. there was significant difference in the effective rate between group A and group C. there was significant difference in the effective rate between group B and group C. there was no significant difference in the effective rate between group A and group C. there was no significant difference in the effective rate between group B and group C. Conclusion Etilmicin sulfate is a preferred antibiotic in the treatment of liver cirrhosis complicated with infection.
【作者单位】：吴忠市人民医院消化内科;第四军医大学西京医院急救中心;
【基金】：国家自然科学基金资助项目(81070063)
【分类号】：R57

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