脉络膜新生血管性疾病的分布及荧光素血管造影特征

发布时间：2018-02-07 13:28

本文关键词： 脉络膜新生血管年龄相关性黄斑变性中心性渗出性脉络膜视网膜病变病理性近视荧光素眼底血管造影　出处：《北京协和医学院》2010年硕士论文　论文类型：学位论文

【摘要】：目的探讨脉络膜新生血管(choroidal neovascularization,CNV)在不同眼底疾病中的分布及荧光素眼底血管造影(fundus fluorescein angiography,FFA)特征。方法回顾性分析2001年01月09日至2009年08月31日在北京协和医院眼科行FFA检查的8500例患者资料,筛选出湿性AMD、PM、CEC和其他并发CNV的427例患者,分析这些疾病的分布和FFA特点。结果 CNV性疾病总共427例,其中湿性年龄相关性黄斑变性(age-related macular degeneration, AMD)209例(254只眼),中心性渗出性脉络膜视网膜病变(central exudative chorioretinopathy,CEC)132例(139只眼),病理性近视(pathologic myopia, PM)48例(61只眼),其他CNV性疾病38例。湿性AMD占CNV性疾病总数的比例为48.9%,CEC为30.9%,PM为11.2%,其他CNV性疾病占9%。湿性AMD患者年龄43-89岁,平均年龄64.2岁；男性106例,女性103例；单眼164例,双眼45例。CEC患者年龄10-52岁,平均年龄27.4岁；男性39例,女性93例；单眼125例,双眼7例。PM患者年龄19-68岁,平均年龄47.3岁；男性15例,女性33例；,单眼35例,双眼13例。湿性AMD患眼总数254只眼,其中隐匿性CNV 161只眼,占63.4%;典型性CNV 46只眼,占18.1%；瘢痕性CNV 47只眼,占18.5%。结论北京协和医院眼科FFA资料分析表明,CNV性疾病中最常见的是湿性AMD,其次是CEC和PM。湿性AMD中隐匿性CNV最多,占63.4%。患者平均年龄最大的是湿性AMD,其次是PM和CEC。湿性AMD患者男女比例接近,CEC患者和PM患者均为女性多于男性。湿性AMD、CEC和PM三种疾病,患病眼别均是单眼多于双眼。
[Abstract]:Purpose. To investigate the distribution of choroidal neovascularization (CNV) in different fundus diseases and the features of fundus fluorescein angiographic angiography (FFA) in choroidal neovascularization. Method. From January 9th 2001 to August 31st 2009, the data of 8500 patients who underwent FFA examination in Peking Union Hospital were retrospectively analyzed. The distribution and FFA characteristics of these diseases were analyzed. Results. There were 427 cases of CNV disease. There were 254 eyes with AMD)209, 139 eyes with central exudative chorioretinopathy, 61 eyes with pathologic myopia, 61 eyes with PM)48 and 38 cases with other CNV diseases, including wet age-related macular degeneration.The central exudative chorioretinopathy (CEC) of central exudative chorioretinopathy was found in 139 eyes, pathologic myopia in pathological myopia, PM)48 in 61 eyes, and other CNV diseases in 38 cases. The proportion of total CNV disease is 48.9%, PM is 11.2and other CNV disease is 9.The age of patients with wet AMD is 43-89 years old. The mean age was 64.2 years, 106 males, 103 females, 164 monocular patients, 45 CEC patients aged 10-52 years, 39 males, 93 females, 125 monocular patients and 7 patients with binocular .PM, with an average age of 47.3 years (ranging from 19 to 68 years). 15 cases were male, 33 cases were female, 35 cases were monocular, 13 cases were binocular. There were 254 eyes with wet AMD, including 161 eyes with occult CNV (63.4%), 46 eyes with typical CNV (18.1 eyes) and 47 eyes with scar CNV (18.5B). Conclusion. According to the analysis of FFA data of ophthalmology in Peking Union Hospital, the most common disease was wet CNV, followed by CEC and PM.The occult CNV in wet AMD was the most common. The average age of the patients was higher than that of PM and CEC.The ratio of male to female was higher than that of male in wet AMD.
【学位授予单位】：北京协和医学院
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R773

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