真菌性角膜炎患者手术治疗效果分析

发布时间：2018-02-12 11:16

本文关键词： 真菌性角膜炎羊膜板层角膜切削穿透性角膜移植　出处：《中华医院感染学杂志》2014年09期 　论文类型：期刊论文

【摘要】：目的观察采用不同手术方法治疗真菌性角膜炎的临床效果,为临床治疗提供参考。方法选择2008年12月-2012年12月眼科收治的真菌性角膜炎患者共186例,患眼186眼,根据不同的手术方式分为4组,A组行单纯板层角膜切削,B组行板层角膜切削联合羊膜覆盖,C组行单纯穿透性角膜移植,D组行穿透性角膜移植联合羊膜覆盖,各组患者随访时间均1年,观察各组术后效果。结果 186例患眼中184眼保留了眼球,其中179例患者在术后随访中视力明显与术前相比有明显提高:A组治疗有效44例有效率93.62%;B组治疗有效47例有效率94.00%;C组治疗有效47例有效率95.92%;D组治疗有效38例有效率95.00%。结论当药物治疗不能控制真菌性角膜炎病程发展时要及时改行手术治疗,彻底将病灶组织清除是保证手术治疗效果的首要条件,术中应用羊膜和结膜瓣覆盖有利于保护创面,利于愈合。
[Abstract]:Objective to observe the clinical effect of different surgical methods in the treatment of fungal keratitis and to provide reference for clinical treatment. Methods 186 cases of fungal keratitis were selected from December 2008 to December 2012. According to the different operation methods, four groups were divided into four groups: group A received lamellar keratectomy and group B underwent lamellar keratectomy combined with amniotic membrane covering. Group D underwent penetrating keratoplasty combined with amniotic membrane covering. All the patients in each group were followed up for 1 year to observe the postoperative results. The visual acuity of 179 cases was obviously improved compared with that before operation. The effective rate of 44 cases in group A was 93.622%. In group B, 47 cases were effective. The effective rate in group C was 94.00%. The effective rate in group C was 95.92%. Group D was effective in 38 cases. 95.00.Conclusion when the course of fungal keratitis can not be controlled by drug therapy, the surgical treatment should be carried out in time. Thorough removal of the lesion tissue is the primary condition to ensure the effect of surgical treatment. The application of amniotic membrane and conjunctival flap during the operation is beneficial to the protection of the wound and the healing of the wound.
【作者单位】：绍兴市第二医院眼科;
【基金】：浙江省卫生厅基金资助项目(2013KYA233)
【分类号】：R772.21

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