鼻咽癌放疗患者口腔真菌感染的临床分析

发布时间：2018-02-23 12:59

本文关键词： 鼻咽癌同期放疗口腔真菌感染临床分析　出处：《中华医院感染学杂志》2014年16期 　论文类型：期刊论文

【摘要】：目的分析鼻咽癌放疗患者合并口腔真菌感染的临床特点及治疗效果,为临床治疗提供参考依据。方法选取2009年3月-2012年12月鼻咽癌患者共112例;观察其口腔真菌的感染率,分析发生口腔真菌感染的危险因素以及治疗效果,数据采用SPSS13.0进行分析。结果进行放疗或者同期进行放化疗的鼻咽癌患者发生口腔感染率74.11%,单纯放疗患者口腔真菌感染率72.15%,同期进行放化疗患者的感染率为78.79%;口腔真菌感染患者口腔pH值6时感染率86.75%,住院时间40d患者的感染率有69.88%,使用≥2种抗菌药物感染患者感染率为73.49%。结论鼻咽癌患者在接受放疗时应注意口腔清洁卫生,采用碳酸氢钠进行漱口,保持口腔pH6,避免并发口腔真菌感染。
[Abstract]:Objective to analyze the clinical characteristics and therapeutic effect of radiotherapy for nasopharyngeal carcinoma (NPC) patients with oral fungal infection. Methods 112 patients with nasopharyngeal carcinoma from March 2009 to December 2012 were selected and their oral fungal infection rate was observed. To analyze the risk factors and therapeutic effect of oral fungal infection. Data were analyzed by SPSS13.0. Results the oral infection rate was 74.11 in patients with nasopharyngeal carcinoma and 72.15 in patients with radiotherapy alone, and 78.79 in patients with radiotherapy and chemotherapy. The infection rate of patients with fungal infection was 86.75 6:00. The infection rate of patients with 40 days of hospitalization was 69.88. The infection rate of patients with infection with more than two antibiotics was 73.49.Conclusion the patients with nasopharyngeal carcinoma should pay attention to oral hygiene when receiving radiotherapy. Use sodium bicarbonate to gargle, maintain oral pH 6, avoid oral fungal infection.
【作者单位】：南阳市中心医院放疗科;
【基金】：河南省卫生厅专项基金资助项目(HW-2010A-101241)
【分类号】：R739.63

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