糖尿病视网膜病变临床相关危险因素分析

发布时间：2018-02-25 01:17

本文关键词： 2型糖尿病视网膜病变危险因素　出处：《新疆医科大学》2010年硕士论文　论文类型：学位论文

【摘要】： 目的:探讨影响2型糖尿病视网膜病变发生、发展的相关危险因素。方法:收集我院自2006年12月～2009年1月内分泌科诊断为2型糖尿病114例住院患者资料,根据眼底荧光造影将其分为无糖尿病视网膜病变组(NDR组)和糖尿病视网膜病变组(DR组),并对其分别监测血压、空腹血糖(FBG)、餐后2h血糖(2hBG)、糖化血红蛋白(HbA1c)、甘油三酯(TG)、血清总胆固醇(TC)、低密度脂蛋白(LDL)、收缩压(SBP)、舒张压(DBP)、24小时尿微量蛋白、血尿素(BU)、血肌酐(Cr)等指标,以及询问糖尿病病程,进行分析、比较两组间差异,以及分析各因素与DR之间的相关性。结果:DR组的年龄、糖尿病病程、FBG、TC、LDL、SBP、DBP、24h尿微量蛋白与非DR组相比,差异有统计学意义(P 0.05) ,其他因素在两组间差异无统计学意义(P 0.05)。多因素非条件Logistic回归结果显示:年龄、FBG与糖尿病视网膜病变存在明显相关性(P 0.05),可认为是2型糖尿病视网膜病变的独立危险因素。结论:年龄大,糖尿病病程长,高血糖、高血脂、高血压、尿微量蛋白的异常为糖尿病视网膜病变的危险因素,糖尿病患者严格控制血糖、血脂、血压可能延缓糖尿病视网膜病变的发生、发展。
[Abstract]:Objective: to investigate the risk factors related to the occurrence and development of type 2 diabetic retinopathy. Methods: from December 2006 to January 2009, 114 inpatients with type 2 diabetes diagnosed by the Endocrinology Department in our hospital were collected. According to fundus fluorescein imaging, the patients were divided into two groups: nondiabetic retinopathy group (NDR group) and diabetic retinopathy group (Dr group), and their blood pressure was monitored. Fasting blood glucose (FBG), 2 h postprandial blood glucose (2hBGG), glycosylated hemoglobin (HbA1cU), triglyceride (TGG), serum total cholesterol (TC), low density lipoprotein (LDL), systolic blood pressure (SBP), diastolic blood pressure (DBP), 24 hour urine microprotein, blood urea bun (bun), serum creatinine (Cr), etc., and asking about the course of diabetes. The differences between the two groups and the correlation between the factors and Dr were analyzed. Results there were significant differences in the age, the course of diabetes and the 24 hours urine microprotein between the two groups compared with the non-Dr group (P 0.05). There was no significant difference in other factors between the two groups (P 0.05). The results of multivariate conditional Logistic regression showed that there was a significant correlation between age and diabetic retinopathy (P 0.05), which could be considered as an independent type 2 diabetic retinopathy. Risk factors. Conclusion: age, The long course of diabetes, hyperglycemia, hyperlipidemia, hypertension and abnormal urine microalbumen are the risk factors of diabetic retinopathy, diabetes patients strictly control blood glucose, blood lipid, blood pressure may delay the occurrence of diabetic retinopathy, Development
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R774.1

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