鼻喷激素联合鼻腔冲洗对儿童上气道咳嗽综合征的疗效观察

发布时间：2018-02-27 04:17

本文关键词： 糖皮质激素类鼻腔冲洗上气道咳嗽综合征　出处：《中国全科医学》2014年02期 　论文类型：期刊论文

【摘要】：目的探讨鼻喷激素联合鼻腔冲洗治疗儿童上气道咳嗽综合征(UACS)的疗效。方法选择2010年6月—2013年6月在本科门诊就诊的咳嗽超过2周的239例患儿,且排除胃食管反流、咳嗽变异性哮喘(CVA)等心肺部疾病,行电子纤维鼻咽镜检查、鼻窦冠状位CT扫描、皮肤过敏原点刺试验(SPT)等检查后符合UACS诊断标准,并将其分为治疗组(129例)和对照组(110例)。治疗组联合使用鼻喷激素和鼻腔冲洗治疗,对照组单纯使用鼻喷激素治疗。评估治疗组与对照组的治疗效果,并采用主观症状评分记录鼻喷激素联合鼻腔冲洗治疗前后的喷嚏、流涕、鼻塞、咳嗽等评分。结果治疗组(显效90例,好转24例,无效15例)疗效优于对照组(显效49例,好转38例,无效23例)(P0.05)。治疗后治疗组鼻痒、咳嗽、鼻塞、喷嚏、流涕、咽痒症状均较治疗前好转(P0.05)。结论鼻喷激素联合鼻腔冲洗对UACS引起的儿童慢性咳嗽可起到良好的治疗作用,为临床治疗提供了理论依据。
[Abstract]:Objective to investigate the efficacy of nasal spray hormone combined with nasal lavage in the treatment of upper airway cough syndrome (UACSs) in children. Methods 239 children with cough more than 2 weeks from June 2010 to June 2013 were selected and their gastroesophageal reflux was excluded. Patients with cough variant asthma (CVA) and other heart and lung diseases were examined with electronic fiberoptic nasopharyngoscope, CT scan of paranasal sinus coronal position, skin allergen prick test and so on, which met the diagnostic criteria of UACS. It was divided into treatment group (n = 129) and control group (n = 110). The treatment group was treated with nasal spray hormone and nasal cavity irrigation, while the control group was treated with nasal spray hormone alone. Subjective symptom score was used to record the scores of sneezing, runny, nasal congestion and cough before and after the treatment. Results the curative effect of the treatment group (90 cases of remarkable effect, 24 cases of improvement and 15 cases of ineffective) was better than that of the control group (49 cases). After treatment, the symptoms of nasal itch, cough, nasal congestion, sneezing, runny and pharyngeal itch in treatment group were better than those before treatment. Conclusion nasal spray hormone combined with nasal lavage can play a good role in treating chronic cough caused by UACS in children. It provides a theoretical basis for clinical treatment.
【作者单位】：浙江省余姚市人民医院耳鼻喉头颈外科;
【分类号】：R765

【参考文献】