绷带型角膜接触镜与眼部药物治疗复发性角膜上皮糜烂的疗效比较

发布时间：2018-03-03 20:32

本文选题：角膜上皮糜烂　切入点：复发性　出处：《南京医科大学学报(自然科学版)》2014年11期 　论文类型：期刊论文

【摘要】：目的 :研究配戴绷带型角膜接触镜治疗复发性角膜上皮糜烂是否较眼部药物治疗更安全和有效。方法 :选择27例30眼复发性角膜上皮糜烂患者,随机配戴绷带型角膜接触镜或进行眼部药物治疗,简称接触镜组和药物组。接触镜组连续配戴绷带型角膜接触镜3个月,每2周更换1次,药物组使用贝复舒眼用凝胶每日3次,睡前1次,连续3个月,两组在角膜上皮修复前均使用可乐必妥滴眼液每日4次预防感染,角膜上皮修复后接触镜组继续使用可乐必妥滴眼液每日2次预防感染,药物组停止使用可乐必妥滴眼液。两组研究对象在接受治疗后定期复诊,随访时间9个月。记录治疗前后最佳矫正视力、角膜上皮生长情况以及对眼部不适进行评分。结果:接触镜组完全治愈率(81.25%)高于药物组(42.86%),差异有统计学意义(P=0.036)。接触镜组平均治愈时间[(4.3±0.3)周]较药物组[(8.5±0.1)周]短,差异有统计学意义(P=0.043)。治疗前、后最佳矫正视力之间的差值和眼部不适评分治疗前后的差值两组间比较均无统计学意义(P均0.05)。结论:配戴绷带型角膜接触镜是治疗复发性角膜上皮糜烂的一种安全且有效的方法。
[Abstract]:Objective: to study the efficacy and safety of bandage contact lens in the treatment of recurrent corneal epithelial erosion. Methods: 27 cases (30 eyes) of recurrent corneal epithelial erosion were selected. The contact lens group and the drug group were used to wear the bandaged contact lens for 3 months and to change it every 2 weeks. In the drug group, three times a day and one time before bedtime for 3 months, the two groups were treated with clonidine eye drops 4 times a day before the corneal epithelium was repaired. After the corneal epithelium was repaired, the contact lens group continued to use clonidine eye drops twice a day to prevent infection, and the drug group stopped using clopidone eye drops. The follow-up time was 9 months. The best corrected visual acuity was recorded before and after treatment. Results: the complete cure rate of contact lens group (81.25%) was higher than that of drug group (42.86%), the difference was statistically significant (P < 0.036 6). The average cure time of contact lens group [4.3 卤0.3 weeks] was shorter than that of drug group [8.5 卤0.1 weeks]. The difference was statistically significant (P < 0.043). The difference between the best corrected visual acuity after treatment and the difference between the two groups before and after treatment had no statistical significance (P < 0.05). Conclusion: wearing bandage contact lens is an effective method for the treatment of recurrent corneal epithelial erosion. A complete and effective method.
【作者单位】：杭州师范大学附属医院眼科;
【分类号】：R772.21

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