21例蚕蚀性角膜溃疡的临床分析

发布时间：2018-03-05 15:04

本文选题：角膜溃疡　切入点：流行病学　出处：《吉林大学》2011年硕士论文　论文类型：学位论文

【摘要】：目的分析蚕蚀性角膜溃疡的临床流行病学特点、相关的因素以及比较几种治疗方法的效果。方法通过对21例(28眼)的患者年龄、性别、溃疡浸润深度、溃疡浸润范围、溃疡穿孔、免疫学检查的情况,以及单纯药物、非角膜移植手术+药物、角膜移植手术+药物的3个治疗组的疗效进行分析。结果男女比例为2：1,男性平均发病年龄57岁,女性平均发病年龄62.7岁,双眼患者7例(33.3%),角膜病变范围占角膜缘1/3者9眼,1/3-2/3者12眼,2/3者7眼,角膜溃疡总的穿孔率14.3%。单纯药物治疗的有效率为58.8%,非角膜移植手术+药物治疗的有效率为66.7%,角膜移植手术+药物治疗的有效率为66.7%。结论多种不同药物以及非角膜移植手术的综合应用可提高治疗的有效性。
[Abstract]:Objective to analyze the clinical epidemiologic characteristics, related factors and the effect of several treatment methods of corneal ulcer caused by silkworm erosion. Methods the age, sex, depth of ulcer infiltration, ulcers infiltration range, ulcer perforation, immunological examination, and drugs alone, non-keratoplasty drugs were used in 21 patients (28 eyes). The curative effect of 3 groups treated with drugs for corneal transplantation was analyzed. Results the male / female ratio was 2: 1, the average age of male was 57 years old, the average age of female was 62.7 years old, the mean age of onset was 62.7 years old, 7 cases of binocular patients were 33. 3%. The range of corneal lesion was 1/3 eyes, 9 eyes with 1 / 3 / 3 / 3, 12 eyes with 2 / 3 / 3 eyes, 7 eyes with 3 / 3 eyes. The total perforation rate of corneal ulcer was 14.3.The effective rate of drug therapy was 58.8%, that of non-corneal transplantation surgery was 66.7%, and that of corneal transplantation operation was 66.7%. Conclusion the comprehensive application of different drugs and non-keratoplasty can improve the effectiveness of the treatment.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R779.6

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