氪黄激光联合中药治疗非增值型糖尿病性视网膜病变黄斑水肿的临床疗效观察

发布时间：2018-03-05 15:55

本文选题：非增殖型糖尿病性视网膜病变黄斑水肿补阳还五汤　切入点：氪黄激光光凝术　出处：《福建中医药大学》2010年硕士论文　论文类型：学位论文

【摘要】： 目的：观察氪黄激光联合补阳还五汤加减治疗非增殖型糖尿病性视网膜病变黄斑水肿的临床疗效。方法：对非增殖型糖尿病性视网膜病变黄斑水肿40例69只眼,按随机分配到综合治疗组20例35只眼,激光治疗组20例34只眼。综合治疗组应用氪黄激光联合中药方剂(补阳还五汤加减)治疗；激光治疗组单纯应用氪黄激光治疗。观察两组患者视力、黄斑水肿、视网膜出血、渗出、微动脉瘤的改善情况,比较两组的治疗效果。结果：(1)治疗三个月后综合治疗组视力提高与激光治疗组比较有显著性差异(P=0.020,P＜0.05)；(2)两组患者治疗三个月后FFA检查显示黄斑水肿改善情况相比较,两组有非常显著性差异(P=0.034,P＜0.05)；(3)两组患者治疗三个月后OCT显示黄斑中心视网膜水肿厚度与治疗前比较差异均具有显著性(P=0.000,P＜0.01),两组相比较差异具有显著性(P=0.025,P0.05)。综合治疗组的黄斑水肿显著减轻。(4)治疗三个月后综合治疗组与激光治疗组视网膜出血、渗出的有效率分别是88.6%、79.4%。两组相比有显著性差异(P=0.049,P0.05)；(5)治疗三个月后综合治疗组与激光治疗组微动脉瘤消失的有效率分别是85.7%、70.6%,两组相比有显著性差异(P=0.045,P0.05); 结论：1.综合治疗组对非增殖型糖尿病性视网膜病变黄斑水肿的治疗效果优于激光治疗组。2.综合治疗组在改善视功能、减轻黄斑水肿、促进视网膜出血、渗出的吸收,减少微动脉瘤方面的疗效优于激光治疗组。因此,氪黄激光联合补阳还五汤加减治疗非增殖型糖尿病性视网膜病变黄斑水肿可能是较理想的治疗方法。
[Abstract]:Objective: to observe the clinical effect of krypton yellow laser combined with Buyang Huanwu decoction on macular edema of non proliferative diabetic retinopathy. Methods: forty patients (69 eyes) with macular edema of non-proliferative diabetic retinopathy were randomly assigned to 20 cases (35 eyes) in the combined treatment group. The laser treatment group was treated with krypton yellow laser combined with traditional Chinese medicine prescription (Buyang Huanwu decoction), and the laser treatment group was treated with krypton yellow laser only. The visual acuity, macular edema and retinal hemorrhage were observed in the two groups. Exudate, the improvement of microaneurysm, compare the treatment effect between the two groups. Results there was a significant difference in visual acuity between the combined treatment group and the laser treatment group after 3 months of treatment (P < 0.05). After three months of treatment, FFA examination showed that macular edema was improved in the two groups. There was a very significant difference between the two groups (P < 0.034 P < 0.05) after three months of treatment, the thickness of central macular retinal edema on OCT was significantly different from that before treatment (P < 0.01), and there was a significant difference between the two groups (P 0.025, P 0.05). After 3 months of treatment, retinal hemorrhage was significantly alleviated in the combined treatment group and laser treatment group. The effective rates of exudation were 88.6 and 79.4, respectively. There was significant difference between the two groups (P0.049 and P0.05) after three months of treatment, the effective rates of microaneurysm disappearance in the combined treatment group and the laser treatment group were 85.7 and 70.6, respectively, and there was a significant difference between the two groups. Conclusion 1. The therapeutic effect of the combined treatment group on macular edema of non-proliferative diabetic retinopathy is better than that of the laser treatment group .2.The combined treatment group can improve the visual function, alleviate the macular edema, promote the absorption of retinal hemorrhage and exudation. Therefore, krypton yellow laser combined with Buyang Huanwu decoction in the treatment of non-proliferative diabetic retinopathy macular edema may be an ideal treatment.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R774.5

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