LASIK术后早期角膜前表面高阶像差变化的临床分析

发布时间：2018-03-07 15:39

本文选题：高阶像差　切入点：角膜磨镶术　出处：《国际眼科杂志》2014年04期 　论文类型：期刊论文

【摘要】：目的:分析准分子激光原位角膜磨镶术(LASIK)术后早期(1d内)角膜前表面高阶像差的变化情况。方法:前瞻性病例研究。应用3D SIRIUS角膜地形图仪采集并分析LASIK手术后100例200眼患者不同时间点(术前、术后5,30,60min及1d)的角膜前表面4mm光学区的各高阶像差的RMS值,并对检查结果进行方差分析。结果:LASIK术后5~60min角膜前表面顶点区各高阶像差均明显增大,但均于术后1d恢复至术前水平,差异无统计学意义(P0.05);在各像差中Z17的RMS值增大幅度最大达1126.98%(P0.01),Z12增加幅度最小为147.92%(P=0.03);各高阶像差增大的峰值不同,根据其特点可分为单峰值期、双峰值和平台型三类;平均角膜中央厚度在术后30,60min较术后5min时明显增加,并在术后1d明显降低。结论:LASIK术后角膜前表面顶点区高阶像差会出现明显增大并于1d内恢复至术前水平。
[Abstract]:Objective: to analyze the changes of high order aberrations on the anterior surface of the cornea within 1 day after laser in situ keratomileusis (LASK). Methods: a prospective case study was carried out. A 3D SIRIUS corneal topography was used to collect and analyze the changes after LASIK operation. 100 patients with 200 eyes at different time points (preoperative, The RMS values of each high-order aberration in the 4mm optical region of the anterior corneal surface of the cornea were analyzed by variance analysis. Results the higher order aberrations of the anterior surface of cornea increased significantly at 560min after the operation, but all recovered to the preoperative level on the 1st day after operation. There was no statistical difference between Z17 and P0.05, the maximum increase amplitude of Z17 in each aberration was 1126.98 and the minimum was 147.92%, and the peak value of higher order aberration was different, according to its characteristics, it could be divided into three types: single peak period, double peak value and platform type. The mean central corneal thickness increased significantly at 30min after operation compared with 5min after operation, and decreased significantly on the 1st day after operation. Conclusion the high order aberration of the anterior surface of cornea will increase significantly after 1: LASIK and recover to the preoperative level within 1 day.
【作者单位】：山西医科大学;北京军区总院;
【分类号】：R779.63

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