氪黄激光联合曲安奈德治疗糖尿病弥漫性黄斑水肿的临床疗效观察

发布时间：2018-03-22 15:17

本文选题：氪黄激光　切入点：曲安奈德　出处：《眼科新进展》2014年08期 　论文类型：期刊论文

【摘要】：目的探讨氪黄激光联合曲安奈德治疗糖尿病弥漫性黄斑水肿的临床疗效。方法糖尿病弥漫性黄斑水肿患者65例(80眼)按照就诊时间的顺序分为治疗组与对照组各40眼,两组均应用氪黄激光进行黄斑区格栅样光凝,需行全视网膜光凝者在黄斑格栅样光凝后进行,在此基础上治疗组给予曲安奈德治疗。结果治疗组与对照组的有效率分别为95.0%和85.0%,组间比较差异有统计学意义(P0.05)。治疗前视网膜厚度治疗组为(632.25±91.25)μm,对照组为(635.21±17.25)μm,两组差异无统计学意义(P=0.696),治疗后都有明显下降,分别为(276.25±17.62)μm和(312.52±93.12)μm,同时期组间比较差异有统计学意义(P0.05)。两组治疗前视力对比无明显差异,治疗后1个月与治疗后3个月都有明显提高,同时期组间比较差异无统计学意义(P0.05)。治疗组与对照组的渗漏消失率分别为52.5%和37.5%,组间比较差异有统计学意义(P0.05)。结论氪黄激光联合曲安奈德治疗糖尿病弥漫性黄斑水肿能有效提高综合疗效,降低视网膜厚度及荧光渗漏。
[Abstract]:Objective to investigate the clinical efficacy of krypton yellow laser combined with triamcinolone acetonide in the treatment of diabetic diffuse macular edema. Methods 65 cases (80 eyes) of diabetic diffuse macular edema (DM) were divided into treatment group (n = 40) and control group (n = 40). Both groups were treated with krypton yellow laser in macular area grid like photocoagulation, and all retina photocoagulation was performed after macular grid photocoagulation. Results the effective rates of triamcinolone acetonide in treatment group and control group were 95.0% and 85.0%, respectively. The difference between the two groups was statistically significant (P 0.05). The retinal thickness before treatment was 632.25 卤91.25 渭 m in the treatment group and 635.21 卤17.25 渭 m in the control group. There was no statistically significant difference in P0. 696, and there was a significant decrease in P0. 696 after treatment. The visual acuity of the two groups was 276.25 卤17.62 渭 m and 312.52 卤93.12 渭 m, respectively. There was no significant difference in visual acuity between the two groups before and after treatment (P 0.05). The visual acuity of the two groups increased significantly 1 month after treatment and 3 months after treatment. There was no significant difference between the two groups in the same period (P 0.05). The leakage disappearance rates of the treatment group and the control group were 52.5% and 37.5%, respectively. There was significant difference between the two groups (P 0.05). Conclusion Krypton yellow laser combined with triamcinolone acetonide is effective in the treatment of diffuse macular disease in diabetes mellitus. Edema can effectively improve the comprehensive curative effect. Reduce retinal thickness and fluorescent leakage.
【作者单位】：中山大学中山眼科中心海南眼科医院三病区;
【分类号】：R587.2;R774.5

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