无ROP早产儿视盘周围视网膜神经纤维层及黄斑区视网膜和脉络膜厚度分析

发布时间：2018-03-23 03:24

本文选题：光学相干断层扫描　切入点：脉络膜　出处：《眼科新进展》2015年09期 　论文类型：期刊论文

【摘要】：目的应用光学相干断层扫描(optical coherence tomography,OCT)测量早产儿视盘周围视网膜神经纤维层(retinal nerve fiber layer,RNFL)、黄斑中心凹处视网膜及黄斑中心凹下脉络膜的厚度,了解早产儿视网膜及脉络膜的结构特点。方法 2006年9月至2008年9月在南方医科大学珠江医院出生的31例(62眼)无早产儿视网膜病变(retinopathy of prematurity,ROP)的早产儿为早产儿组,同期出生的35例(70眼)足月儿为足月儿组。应用频域OCT行视盘环形扫描,测量不同象限和不同钟点范围的RNFL厚度并计算全周平均RNFL厚度;应用传统扫描方式和深度扫描图像增强技术对被检者眼黄斑中心凹水平和垂直方位进行扫描,测量黄斑中心凹处视网膜及中心凹下脉络膜厚度。结果早产儿各象限及全周平均RNFL厚度均较足月儿薄,其中下方、鼻侧及全周平均RNFL厚度与对照组比较差异均有统计学意义(均为P0.01)。早产儿黄斑中心凹处视网膜厚度比足月儿厚,差异有统计学意义(P0.001)。早产儿黄斑中心凹下脉络膜厚度与足月儿相比差异无统计学意义(P0.05)。结论早产儿RNFL厚度较足月儿薄,黄斑中心凹处视网膜厚度比足月儿厚,黄斑中心凹下脉络膜厚度无明显差异。
[Abstract]:Objective to measure the thickness of retinal nerve fiber layer in preterm infants with optical coherence tomography (Oct) at the central fovea of the macula and the central fovea of the macula, and to measure the thickness of the retina and the subfoveal choroid of the central fovea of the macula. Methods from September 2006 to September 2008, 31 cases (62 eyes) born in Zhujiang Hospital of Southern Medical University with no retinopathy of prematurityROP) were included in the premature infant group. Thirty-five full-term infants (70 eyes) were born in the same period. OCT was used to scan the optic disc in frequency domain. The thickness of RNFL was measured in different quadrants and different hours, and the mean RNFL thickness was calculated. The horizontal and vertical azimuth of macular fovea were scanned by traditional scanning method and depth scanning image enhancement technique. Results the mean thickness of RNFL in each quadrant and whole week of preterm infants was thinner than that of full-term infants. The mean RNFL thickness of nasal side and whole week was significantly different from that of the control group (P0.01). The retinal thickness at fovea of macular center of premature infants was thicker than that of full-term infants. There was no significant difference in the thickness of subfoveal choroid between preterm and full-term infants. Conclusion the thickness of RNFL in premature infants is thinner than that in term infants, and the retinal thickness at fovea of macular center is thicker than that of full-term infants. There was no significant difference in the thickness of choroid in central fovea of macula.
【作者单位】：南方医科大学珠江医院眼科;南方医科大学附属深圳宝安人民医院骨关节科;
【分类号】：R774.1

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