糖化血红蛋白A1c与突发性耳聋的相关性研究

发布时间：2018-03-25 09:04

本文选题：糖化血红蛋白　切入点：突发性耳聋　出处：《糖尿病新世界》2015年09期

【摘要】：目的研究探讨糖化血红蛋白A1c与突发性耳聋之间的相关性。方法选取该院收治的突发性耳聋患者140例作为研究对象,按照患者的糖化血红蛋白检测结果 ,以6.5%为分界,Hb A1c≥6.5%为观察组,共70例(89耳),Hb A1c6.5%为对照组,共70例(77耳),分别对两组患者进行听力学检查,并比较治疗前两组患者患耳听力下降程度、不同频率的听阈损失情况。患者均给予针对病因和病症的综合性治疗,测定不同频率的听阈听力改善情况,并比较治疗后两组患者总的临床效果以及。结果治疗前两组患者的听力下降程度、不同频率的听阈损失情况之间的比较均差异有统计学意义(P0.05);治疗后观察组与对照组治疗后的有效率分别为40.0%和78.6%,观察组显著低于对照组,比较差异有统计学意义(P0.05)。结论 Hb A1c升高会加重突发性耳聋听力下降程度,影响突发性耳聋患者的预后。给予突发性耳聋患者以糖化血红蛋白检测可以为突发性耳聋预后的评价以及治疗方案的确定提供依据。
[Abstract]:Objective to investigate the correlation between glycosylated hemoglobin A1c and sudden deafness. Methods the hospital treated 140 cases of sudden deafness patients as the research object, in accordance with the HbA1c test results of patients, divided by 6.5%, Hb A1c = 6.5% for the observation group, a total of 70 cases (89 ears), Hb control group A1c6.5%, a total of 70 cases (77 ears), were audiological examination of two groups of patients, and compare the two groups before treatment of patients suffering from hearing loss, hearing loss in different frequency. The patients were given comprehensive treatment for the cause and conditions, determination of different frequency hearing threshold to improve the situation, and after treatment between the two the total group of patients the clinical effect and degree. The results of the two groups before treatment was statistically significant between hearing loss, hearing loss situation of different frequency difference (P0.05); after treatment, observation group and control group treatment After treatment the effective rate were 40% and 78.6%, the observation group was significantly lower than the control group, the difference was statistically significant (P0.05). Conclusion Hb increased A1c can aggravate the hearing of sudden deafness decreased, affecting the prognosis of patients with sudden deafness. For patients with sudden deafness with HbA1c test can provide the basis for evaluation of prognosis of sudden deafness and determination of treatment.

【作者单位】：赤峰市医院;大连医科大学附属二院;
【分类号】：R587.1;R764.437

【共引文献】