老年阻塞性睡眠呼吸暂停综合征多导睡眠图与认知功能的相关性

发布时间：2018-03-26 06:36

本文选题：阻塞性睡眠呼吸暂停综合征　切入点：多导睡眠图　出处：《中国老年学杂志》2014年20期

【摘要】：目的探讨老年阻塞性睡眠呼吸暂停综合征(低通气综合征,OSAS)患者多导睡眠图与认知功能的相关性。方法以该院42例老年OSAS患者为观察对象,另以40例具有可比性的非OSAS患者为对照,比较两组PSG及认知功能,并对OSAS患者PSG和认知功能的相关性进行pearson相关性分析。结果 (1)OSAS组患者入睡后觉醒次数、呼吸暂停低通气指数(AHI)、Ⅲ+Ⅳ期、呼吸紊乱指数、氧减指数OSAS组高于对照组(P0.05);最低血氧饱和度(SaO2)、平均SaO2OSAS组低于对照组(P0.05);(2)OSAS组MMSE、MoCA、画钟实验、2 min后延迟记忆与对照组相比差异具有统计学意义(P0.05);(3)相关性分析发现,MMSE与最低SaO2和平均SaO2具有相关性(P0.05);MoCA与最低和呼吸紊乱指数具有相关性(P0.05);画钟实验与平均SaO2具有相关性(P0.05);符号数字测验与入睡后觉醒次数、最低SaO2具有相关性(P0.05);2 min后延迟记忆与入睡后觉醒次数具有相关性(P0.05)。结论老年OSAS患者存在认知功能障碍,其发生可能与低氧血症、呼吸紊乱有关。
[Abstract]:Objective to investigate the correlation between polysomnography and cognitive function in elderly patients with obstructive sleep apnea syndrome (OSAS). The correlation between PSG and cognitive function in 40 patients with OSAS was analyzed by pearson. Results the frequency of wakefulness after falling asleep was analyzed in 40 patients with OSAS. Apnea hypopnea index, apnea hypopnea index, apnea hypopnea index, apnea hypopnea index, apnea hypopnea index, The oxygen reduction index in OSAS group was higher than that in control group (P 0.05), and the lowest oxygen saturation in SaO2OSAS group was lower than that in control group (P 0.05). The delayed memory after 2 min of clock drawing experiment was significantly higher than that in control group (P 0.05). The correlation analysis showed that MMSE was lower than that in control group (P < 0.05). SaO2 and average SaO2 were correlated with lowest and respiratory disturbance index (P0.05), clock drawing experiment correlated with average SaO2 (P0.05), symbol number test and the times of awakening after falling asleep. There was a correlation between the delayed memory after 2 min and the number of awakening after falling asleep. Conclusion there is cognitive dysfunction in elderly patients with OSAS, which may be related to hypoxemia and respiratory disorder.
【作者单位】：海南医学院附属医院;
【分类号】：R766

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