等离子射频消融术治疗腺样体肥大对儿童免疫功能的影响

发布时间：2018-04-02 08:47

本文选题：腺样体肥大　切入点：免疫功能　出处：《广东医学》2014年11期

【摘要】：目的探讨低温等离子射频消融系统治疗腺样体肥大对儿童免疫功能的影响。方法 30例腺样体肥大且行等离子射频消融术治疗的儿童作为观察组,同期来我院进行体检的25例正常儿童作为对照组,检测两组患儿血清IgM、IgG、IgA、C3、C4水平,并在鼻内镜下比较腺样体治疗前后的大小变化。结果随访半年以上,全部患者腺样体恢复正常大小,黏膜完整,临床症状消失或减轻,无术后严重并发症出现。小于6岁患儿术前血清IgM、IgG、IgA水平高于对照组,差异有统计学意义(P0.05),术后1周血清IgM、IgG、IgA水平低于术前1周水平,术后1个月恢复正常。大于6岁患儿血清指标与对照组比较差异无统计学意义(P0.05),手术前后补体水平变化差异无统计学意义(P0.05)。结论等离子低温射频消融治疗腺样体肥大具有微创、安全、便捷、出血少、痛苦小等优点,在有效改善患儿症状的情况下,对儿童免疫功能影响较小。
[Abstract]:Objective to investigate the effect of low temperature plasma radiofrequency ablation system on immune function of children with adenoid hypertrophy. Methods 30 children with adenoid hypertrophy treated by plasma radiofrequency ablation were used as observation group. In the same period, 25 normal children who underwent physical examination in our hospital were used as control group. The serum IgMN IgGG titer C 3 C 3 C 4 levels were measured, and the size changes before and after adenoid therapy were compared under nasal endoscope. Results the follow-up was more than half a year. All patients recovered to normal size, mucosal integrity, clinical symptoms disappeared or alleviated, and no serious postoperative complications occurred. The serum IgMN IgGG IgA levels in children younger than 6 years old were higher than those in the control group. The difference was statistically significant (P 0.05), and the level of IgG A in serum 1 week after operation was lower than that at 1 week before operation. There was no significant difference in serum index between children older than 6 years old and control group, and there was no significant difference in complement level before and after operation. Conclusion Plasma hypothermia radiofrequency ablation is minimally invasive in the treatment of adenoid hypertrophy. It is safe, convenient, less bleeding and less painful. It has little effect on children's immune function under the condition of effective improvement of children's symptoms.
【作者单位】：暨南大学医学院附属第四医院;广东省广州市红十字会医院耳鼻咽喉科;广东省广州市红十字会医院检验科;
【基金】：广州市医药卫生科技项目(编号:20121A010002)
【分类号】：R766

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