泪膜功能对原发性翼状胬肉活动度的影响

发布时间：2018-04-05 04:24

  本文选题：翼状胬肉/病理生理学　切入点：泪膜　出处：《眼科》2015年01期

【摘要】：目的评价泪膜功能对原发性翼状胬肉活动度的影响。设计前瞻性比较性病例系列。研究对象2012年8月至2013年2月广东省中山市南朗医院原发性单眼翼状胬肉患者53例。方法纳入翼状胬肉静止期患者14例、活动期患者39例。所有患者进行Schirmer试验、泪膜破裂时间(BUT)及结膜印迹细胞学检查。Logistic回归分析胬肉活动性与患者年龄、性别、泪膜检查结果的关系。主要指标Schirmer试验、BUT、结膜杯状细胞计数结果。结果静止期与活动期翼状胬肉患者Schirmer试验分别为(9.43±2.28)mm、(8.67±2.14)mm(P=0.267);BUT分别为(8.79±1.97)s、(5.05±2.14)s(P=0.000);结膜杯状细胞数量分别是(38.79±2.83)个/10个高倍视野、(32.74±3.30)个/10个高倍视野(P=0.000)。Logistic回归分析显示仅BUT对翼状胬肉是否活动有一定影响(P=0.01)。结论翼状胬肉生长状态与患者眼表状态相关,活动期患者较静止期患者泪膜功能差。
[Abstract]:Objective to evaluate the effect of tear film function on the activity of primary pterygium.Design prospective comparative case series.Participants 53 patients with primary monocular pterygium from August 2012 to February 2013 in Nanlang Hospital Zhongshan City Guangdong Province.Methods 14 patients with static pterygium and 39 patients with active pterygium were included.All patients underwent Schirmer test, tear film rupture time (but) and conjunctival blotting cytology. Logistic regression analysis was used to analyze the relationship between pterygium activity and age, sex and tear film examination results.Main outcome measures Schirmer test and conjunctival goblet cell count.缁撴灉闈欐�㈡湡涓庢椿鍔ㄦ湡缈肩姸鑳�鑲夋偅鑰匰chirmer璇曢獙鍒嗗埆涓，

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