无创正压通气对OSAHS患者脑血流的影响

发布时间：2018-04-13 13:32

本文选题：阻塞性睡眠呼吸暂停低通气综合征 + 持续无创正压通气　；参考：《江苏医药》2014年23期

【摘要】：目的探讨无创正压通气对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的脑血流的影响。方法 26例初治OSAHS患者(A组),11例同期体检者作为对照(B组)。受试者均进行多导睡眠图(PSG)监测,A组确诊OSAHS,B组排除OSAHS。采用经颅多普勒超声(TCD)检查测定A组治疗前和持续无创正压通气6个月和12个月时的脑血流和脑血管狭窄情况,分析脑血流减慢和脑血管狭窄改善病例,记录脑血管事件的发生情况。结果与治疗前比较,A组治疗6个月和12个月脑血流速度减慢的病例明显减少(42.3%和30.8%vs.84.6%)(P0.01),脑血管狭窄病例亦明显减少(26.9%和19.2%vs.57.7%)(P0.05)。A组26例患者,治疗期间均无脑梗死、脑出血等相关脑血管事件的发生。结论无创正压通气有助于改善OSAHS患者的脑血流,预防脑血管事件的发生。
[Abstract]:Objective to investigate the effect of noninvasive positive pressure ventilation on cerebral blood flow in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods 26 patients with OSAHS were treated as control group (n = 11).All subjects were monitored by PSG (polysomnography). OSAHS was excluded from OSAHS B group.The cerebral blood flow and cerebral vascular stenosis were measured by transcranial Doppler echocardiography (TCD) before treatment and at 6 and 12 months after continuous noninvasive positive pressure ventilation in group A, and the cases of cerebral blood flow slowing and improvement of cerebrovascular stenosis were analyzed.Record the occurrence of cerebrovascular events.Results compared with those before treatment, the cerebral blood flow velocity in group A decreased significantly by 42.3% and 30.8vs.84.6P 0.01, and the number of patients with cerebrovascular stenosis decreased by 26.9% and 26 cases in 19.2%vs.57.7%)(P0.05).A group respectively. There was no cerebral infarction during the treatment.Cerebral hemorrhage and other related cerebrovascular events.Conclusion non-invasive positive pressure ventilation can improve cerebral blood flow and prevent cerebrovascular events in patients with OSAHS.
【作者单位】：无锡市第三人民医院神经内科;无锡市第三人民医院呼吸病科;
【分类号】：R766

【参考文献】