视网膜分支静脉阻塞与眼轴、前房深度的相关性研究

发布时间：2018-04-18 06:32

本文选题：视网膜分支静脉阻塞 + 眼轴长度　；参考：《大连医科大学》2011年硕士论文

【摘要】：目的:视网膜分支静脉阻塞(BRVO)是最常见的视网膜血管性疾病之一,是临床常见的致盲性眼病。其病因复杂,危险因素多样,通常发生在伴有高血压,动脉硬化,糖尿病等系统性疾病的老年人。视网膜分支静脉阻塞的发病机制是多种因素参与的病理生理过程,目前尚不十分清楚。本次研究探讨视网膜分支静脉阻塞与眼轴长度及前房深度的关系。方法:随机抽取2009年3月至2010年10月在大连医科大学附属第一医院眼科诊治的45例患者(90只眼),BRVO眼45例(45只眼),来我院体检者45例(均无眼部疾病)作为对照组。分别对其进行彩色眼底照相及荧光血管造影(FFA)检查并分组。BRVO眼45只眼为组1,其对侧眼(健眼)45只眼为组2,对照组45只右眼为组3,对照组45只左眼为组4。应用光学相干生物测量仪-IOL Master对各组眼轴和前房深度进行测量,并进行统计学分析,对照组与病例组年龄和性别相匹配。结果:BRVO组阻塞眼的平均眼轴长度为(22.69±0.99)mm,对侧眼平均眼轴长度为(22.78±1.24)mm,经统计学分析,差异无显著性(t=0.355, P㧐0.05);对照组右眼平均眼轴长度为(23.38±1.32)mm,左眼平均眼轴长度为(23.37±1.27)mm,差异无统计学意义(t=0.017, P㧐0.05),BRVO组阻塞眼和对照组的眼轴长度差异有统计学意义(t=-2.563, t=-2.663, P㩳0.05)。BRVO组阻塞眼的平均前房深度为(2.66±0.26)mm,对侧眼平均前房深度为(2.65±0.30)mm,经统计学分析,差异无显著性(t=0.089, P㧐0.05);对照组右眼平均前房深度为(2.56±0.29)mm,左眼平均前房深度为(2.59±0.30)mm,差异无统计学意义(t=-0.592, P㧐0.05),BRVO组阻塞眼和对照组的前房深度差异无统计学意义(t=1.779, t=1.778, P㧐0.05)。结论:短眼轴可能是一个发展视网膜分支静脉阻塞的危险因素。前房深度和视网膜分支静脉阻塞的关系尚待进一步证实。
[Abstract]:Objective: branch retinal vein occlusion (BRVOO) is one of the most common retinal vascular diseases and is a common blinding ophthalmopathy.Its etiology is complex, the risk factor is diverse, usually occurs in the elderly with hypertension, arteriosclerosis, diabetes and other systemic diseases.The pathogenesis of retinal branch vein occlusion (RVO) is a pathophysiological process in which many factors are involved.This study was to investigate the relationship between retinal branch vein occlusion (RVO) and axial length and anterior chamber depth.Methods: from March 2009 to October 2010, 45 patients with BRVO and 45 patients with BRVO were randomly selected from the first affiliated Hospital of Dalian Medical University as control group.Color fundus photography and fluorescein angiography (FFAA) were performed, and 45 eyes of BRVO were divided into group 1. The contralateral eyes (group 2 of healthy eye group, 45 eyes of control group 3 eyes of right eye and 45 eyes of control group) were divided into two groups: control group (45 eyes) and control group (group 4).The depth of eye axis and anterior chamber were measured by optical coherence biometer (-IOL Master). The age and sex of the control group and the case group were matched.Results the mean axial length of the obstructive eyes and contralateral eyes was 22.69 卤0.99 mm and 22.78 卤1.24 mm, respectively.The average axial length of right eye and left eye were 23.38 卤1.32 mm and 23.37 卤1.27 mm respectively in the control group. There was no significant difference in the mean axial length of the right eye and the left eye. There was no significant difference in the axial length between the two groups. There was significant difference in the axial length of the obstructive eyes between the P?0.05).BRVO group and the control group (t = 2.563, t = 2.663respectively).The mean anterior chamber depth was 2.66 卤0.26mm and the contralateral anterior chamber depth was 2.65 卤0.30mm.The mean anterior chamber depth of right eye and left eye was 2.56 卤0.29 mm and 2.59 卤0.30 mm, respectively. There was no significant difference in anterior chamber depth between the two groups. There was no significant difference in the anterior chamber depth between the two groups. There was no significant difference in the anterior chamber depth between the two groups. There was no significant difference in the anterior chamber depth between the two groups (t 1.779, t 1.778, P = 0.05m), and there was no significant difference in the mean anterior chamber depth between the control group and the control group (P < 0.05), but the mean anterior chamber depth of the right eye was 2.56 卤0.29 mm and that of the left eye was 2.59 卤0.30 mm, respectively.Conclusion: short eye axis may be a risk factor for the development of retinal branch vein occlusion.The relationship between anterior chamber depth and retinal branch vein occlusion needs to be further confirmed.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R774.1

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