不同种类刺激声对国人青年正常人群气导声刺激诱发的颈肌前庭诱发肌源性电位的影响

发布时间：2018-04-22 12:30

本文选题：前庭 + 颈肌前庭诱发肌源性电位　；参考：《临床耳鼻咽喉头颈外科杂志》2015年13期

【摘要】：目的:观察不同种类刺激声音对正常青年人群气导声刺激诱发的颈肌前庭诱发肌源性电位(ACScVEMP)各参数的影响。方法:选择20例(40耳)19~30岁的正常人为研究对象,男10例,女10例。刺激声分别采用500Hz Tone Burst、1 000Hz Tone Burst、Click进行双耳ACS-cVEMP检测,比较各种刺激声下ACScVEMP的引出率、阈值、P1潜伏期、N1潜伏期、P1-N1波间期、振幅及耳间对称性。结果:500Hz Tone Burst的ACS-cVEMP的引出率为97.5%(39/40),1 000Hz Tone Burst的ACS-cVEMP的引出率为87.5%(35/40),Click的引出率为67.5%(27/40)。500Hz Tone Burst与1 000Hz Tone Burst的引出率组间差异无统计学意义(P0.05),500Hz Tone Burst和1 000Hz Tone Burst与Click的引出率组间有差异统计学意义(P0.05),500Hz Tone Burst诱发的ACS-cVEMP的阈值、P1潜伏期、N1潜伏期、P1-N1波间期、振幅较其他2组参数组间对比差异有统计学意义(P0.05),每一波形参数耳间对称性组间波形参数差异无统计学意义。结论:不同刺激声可以对国人正常青年人群ACS-cVEMP的引出率和各波形参数造成影响,500Hz Tone Burst是已知的ACScVEMP的最佳刺激声之一。
[Abstract]:Aim: to observe the effects of different stimuli on the parameters of ACScVEMPs induced by air conduction sound stimulation in normal young people. Methods: 20 normal subjects (10 males and 10 females) aged 1930 years were selected. 500Hz Tone burst 1 000Hz Tone burst Click was used to detect biaural ACS-cVEMP. The extraction rate of ACScVEMP under various stimuli was compared, and the P1-N1 wave interval, amplitude and inter-ear symmetry of P1 latency and N1 latency were compared. Results there was no significant difference in the extraction rate of ACS-cVEMP between 67.5%(27/40).500Hz Tone Burst and 1 000Hz Tone Burst between 67.5%(27/40).500Hz Tone Burst and 1 000Hz Tone Burst (P 0.05500Hz Tone Burst and 1 000Hz Tone Burst and Click). Statistical significance was found in the threshold P1 latency of ACS-cVEMP induced by 500Hz Tone Burst, the N1 latency and the P1-N1 interphase. The amplitude was significantly higher than that of the other two groups (P 0.05), and there was no significant difference in the waveform parameters between the two groups with the symmetry of each waveform parameter. Conclusion: different stimuli can affect the ACS-cVEMP extraction rate and waveform parameters of Chinese normal young people. The 500Hz Tone Burst is one of the best stimulatory sounds known for ACScVEMP.
【作者单位】：西安交通大学医学院第二附属医院耳鼻咽喉头颈外科分院;西安交通大学医学院第二附属医院耳病研究所;西安市第四医院耳鼻咽喉科;
【基金】：国家自然科学基金(No:3013300/C170703) 中央高校基本科研业务费专项资金(No:2012jdhz13) 陕西省重大国际合作项目(No:2013KW-28) 西安市科技攻关项目[No:SF1315(1)] 西安交通大学医学院第二附属医院人才培养专项科研基金[No:RC(GG)201407]
【分类号】：R764.04

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