应用不同的温度行鼻腔冲洗观察变应性鼻炎患者的临床效果
发布时间:2018-04-26 23:18
本文选题:鼻腔冲洗 + 温度 ; 参考:《中国现代医学杂志》2014年23期
【摘要】:目的探讨不同鼻腔冲洗温度对变应性鼻炎患者的临床效果。方法采用随机数字法将200例变应性鼻炎患者平均分为A、B和C 3组,分别给予15、25和40℃生理盐水进行鼻腔冲洗。检测鼻腔冲洗液中白三烯C4、组胺、特异性IgE及嗜酸粒细胞阳离子蛋白(ECP)。3个月随访后对患者临床疗效进行比较。结果治疗后C组患者白三烯C4、组胺较治疗前有明显下降(P0.05),且明显低于A和B两组(P0.05)。治疗后B组、C组喷嚏、鼻塞症状得分较明显低于治疗前(P0.05);C组得分均明显低于A和B两组,B组得分低于A组(P0.05)。3组患者总有效率分别为75.7%、74.6%和95.5%,差异有统计学意义(P0.05)。结论 40℃生理盐水鼻腔冲洗可以通过降低鼻黏膜炎症因子组胺和白三烯C4水平,有效改善患者打喷嚏及鼻塞症状,是适宜的鼻腔冲洗液温度。
[Abstract]:Objective to investigate the clinical effect of different nasal irrigation temperature on allergic rhinitis. Methods 200 patients with allergic rhinitis were randomly divided into two groups: group A (n = 25) and group C (n = 3). To detect leukotriene C4 histamine specific IgE and eosinophil cationic protein in nasal lavage fluid. Results after treatment, leukotriene C4 and histamine in group C were significantly lower than those in group A and B, and were significantly lower than those in group A and B. After treatment, the scores of sneezing and nasal congestion in group B were significantly lower than those in group A and group B before treatment. The total effective rates of group A and group B were 74.6% and 95.5%, respectively. The difference was statistically significant (P 0.05). Conclusion nasal lavage at 40 鈩,
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