高胆红素血症新生儿血清胆红素水平与听力损失程度的相关性分析

发布时间：2018-05-02 14:59

  本文选题：足月新生儿 + 黄疸　； 参考：《听力学及言语疾病杂志》2015年01期

【摘要】：目的探讨高胆红素血症新生儿听力损失程度与血清胆红素水平的相关性。方法对70例足月出生、体重正常、确诊为高胆红素血症的新生儿进行血清胆红素水平及听性脑干反应(ABR)检测,并对其血清胆红素水平、黄疸出现时间与ABR反应阈进行相关性分析。结果 70例患儿中ABR反应阈正常17例,异常53例,其中重度听力损失27例;当血清胆红素342μmol/L时,黄疸出现时间≤48小时组出现重度听力损失的比例高于黄疸出现时间48小时组(P0.05),而血清胆红素值≥342μmol/L时,黄疸出现时间≤48小时组与48小时组轻中度、重度听力损失者比例无明显差异。ABR反应阈异常的53例患儿中,血清胆红素水平与ABR反应阈呈正相关(r=0.041),而黄疸出现的时间与ABR反应阈呈负相关(r=-0.291)。结论高胆红素血症新生儿黄疸出现的时间越早听力损伤的可能性越大,血清胆红素值越高听力损失程度越重。
[Abstract]:Objective to investigate the relationship between the degree of hearing loss and serum bilirubin level in neonates with hyperbilirubinemia. Methods Serum bilirubin level and auditory brainstem response (ABR) were measured in 70 newborns with normal birth weight and hyperbilirubinemia, and serum bilirubin levels were measured. The correlation between the onset time of jaundice and ABR reaction threshold was analyzed. Results among the 70 cases, 17 cases had normal ABR reaction threshold, 53 cases had abnormal hearing loss, 27 cases had severe hearing loss, and while serum bilirubin was 342 渭 mol/L, The incidence of severe hearing loss in jaundice 鈮，

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