血清中TIgE与SIgE在非侵袭性真菌性鼻窦炎2个亚型中的表达及意义

发布时间：2018-05-10 23:04

本文选题：鼻窦炎 + TIg　；参考：《实用医学杂志》2014年19期

【摘要】：目的:探讨血清中TIg E与SIg E在非侵袭性真菌性鼻窦炎2个亚型中的表达及临床意义。方法:回顾性分析我院收治的46例非侵袭性真菌性鼻窦炎患者的临床资料,患者血清中Tlg E、SIg E的表达水平采用Unicap法检测,统计分析血清中TIg E、SIg E的表达水平与非侵袭性真菌性鼻窦炎2个亚型的关系。结果:本组46例非侵袭性真菌性鼻窦炎患者中,真菌球型28例,变态反应型18例。28例真菌球型患者中,血清TIg E呈阳性4例,SIg E呈阳性2例;18例变态反应型患者中,血清Tlg E呈阳性16例,SIg E呈阳性12例。TIg E、SIg E在变态反应型真菌性鼻窦炎患者血清中的表达水平明显高于真菌球型真菌性鼻窦炎患者,差异具有统计学意义(χ2=24.81、18.33,P0.05)。结论:变态反应型真菌性鼻窦炎血清TIg E、SIg E表达水平明显高于真菌球型,对临床分型有一定参考价值。
[Abstract]:Objective: to investigate the expression and clinical significance of TIg E and SIg E in two subtypes of noninvasive fungal sinusitis. Methods: the clinical data of 46 patients with noninvasive fungal sinusitis were retrospectively analyzed. The expression of Tlg Esma sig E in serum was detected by Unicap method. The relationship between the expression of TIg E and two subtypes of noninvasive fungal sinusitis was statistically analyzed. Results: of the 46 cases of noninvasive fungal sinusitis, 28 cases were fungal spherical type, 18 cases were hypersensitive type. 4 cases were positive for serum TIg E, 2 cases were positive for sig E, and 18 cases were allergic type. The expression of TIg E in serum of 16 patients with positive serum Tlg E was significantly higher than that in patients with fungal sinusitis (蠂 2 24. 81 卤18. 3%, P 0. 05, P 0. 05, P 0. 05, P < 0. 05, P < 0. 05, P = 0. 05, P = 0. 05, P = 0. 05, P = 0. 05, P = 0. 05, P = 0. 05, P = 0. 05, P = 0. 05). Conclusion: the level of serum TIg E sig E expression in allergic fungal sinusitis is significantly higher than that in fungal spherical type, which has some reference value for clinical classification.
【作者单位】：遵义医学院附属医院耳鼻喉科;
【基金】：贵州省卫生厅科学技术基金项目(编号:gzwkj2008-1-040)
【分类号】：R765.41

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