高分辨率CT骨密度测量诊断前庭窗型耳硬化症

发布时间：2018-05-13 00:29

本文选题：耳硬化症 + 体层摄影术　；参考：《中国医学影像技术》2014年11期

【摘要】：目的探讨应用高分辨率CT(HRCT)骨密度测量法诊断耳硬化症的应用价值。方法回顾性分析经手术证实的30例耳硬化症患者(耳硬化组)和32名正常对照者(对照组),将ROI置于前庭窗前区进行骨密度CT值测量,并对耳硬化患者进行语频气导和气骨导差听力测试。采用两样本t检验对硬化耳和正常耳骨密度平均CT值进行统计学分析、采用Pearson相关系数分析对耳硬化组平均CT值和听力水平进行分析,并采用ROC曲线分析检测应用CT值诊断耳硬化症的效能。结果硬化组前庭前区CT值范围462.81~2285.00 HU,平均(1372.82±76.50)HU,对照组前庭前区CT值范围1801.71~2680.55HU,平均(2171.42±23.53)HU,耳硬化组平均CT值明显低于正常组(P0.0001);硬化耳平均CT值与语频气导阈值(r=0.18,P=0.19)、与气骨导差(r=-0.01,P=0.93)均无明显相关性。采用平均CT值鉴别耳硬化症的ROC曲线下面积为0.88(P0.05),诊断阈值为1938.29 HU,诊断的敏感度为80.7%,特异度为90.6%。结论骨密度测量对于诊断耳硬化症具有重要应用价值,但其对听力评估的应用有待进一步研究。
[Abstract]:Objective to evaluate the value of high-resolution CT HRCT in the diagnosis of ear sclerosis. Methods the bone mineral density (BMD) of 30 patients with auricular sclerosis (ear sclerosis group) and 32 normal controls (control group) confirmed by surgery were analyzed retrospectively. ROI was placed in the anterior vestibular window area to measure the bone mineral density (BMD). The hearing of patients with ear sclerosis was tested by speech frequency gas conduction and air bone conductance. The average CT value of sclerosing ears and normal ears was statistically analyzed by two samples t test, and the average CT value and hearing level of sclerotic ears were analyzed by Pearson correlation coefficient analysis. ROC curve analysis was used to detect the effectiveness of CT value in the diagnosis of ear sclerosis. Results the CT value range of anterior vestibular area in sclerosing group was 462.81 卤2285.00 HUU, with an average of 1372.82 卤76.50 HUU, while that in control group was 1801.71 卤2680.55 HUU, with an average of 2171.42 卤23.53 HUU, and the average CT value in ear sclerosis group was significantly lower than that in normal group (P0.0001a). There was no significant correlation between the two groups. The area under the ROC curve and the diagnostic threshold were 1938.29 HU. the sensitivity and specificity of the ROC curve were 80.7 and 90.6, respectively. Conclusion Bone mineral density measurement has important value in the diagnosis of ear sclerosis, but its application in hearing assessment needs further study.
【作者单位】：南方医科大学南方医院影像中心;
【分类号】：R816.96;R764.32

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