西黄胶囊联合放疗在鼻咽癌治疗中的临床疗效

发布时间：2018-05-15 16:33

本文选题：西黄胶囊 + 放疗　；参考：《中国实验方剂学杂志》2015年23期

【摘要】：目的:探讨西黄胶囊联合放疗在鼻咽癌患者中的临床治疗效果。方法:选取2012年4月—2014年4月本院诊治的80例鼻咽癌患者资料进行分析,采用随机数字法将患者分为对照组和实验组,对照组采用单一放疗治疗,实验组在对照组治疗基础上联合西黄胶囊治疗,比较两组治疗效果。结果:实验组55%治疗效果理想,高于对照组(42.5%)(P0.05);实验组82.5%临床获益高于对照组(P0.05);两组患者治疗前血清T细胞亚群水平,如:CD3+,CD4+,CD8+以及CD4+/CD8+等指标差异不显著;实验组治疗后CD3+,CD4+,CD8+以及CD4+/CD8+等指标显著低于对照组(P0.05);实验组不良反应发生率为32.5%,低于对照组(42.5%)(P0.05);实验组ADL评分,躯体功能评分,心理功能评分,社会功能评分,均高于对照组(P0.05)。结论:鼻咽癌患者在放疗基础上联合西黄胶囊治疗效果理想,能够提高临床疗效,降低不良反应发生率,值得推广使用。
[Abstract]:Objective: to investigate the clinical effect of Xihuang capsule combined with radiotherapy in patients with nasopharyngeal carcinoma. Methods: the data of 80 patients with nasopharyngeal carcinoma from April 2012 to April 2014 were analyzed. The patients were randomly divided into control group and experimental group. The control group was treated with radiotherapy alone. The experimental group was treated with Xihuang capsule on the basis of control group. Results: 55% of the patients in the experimental group had better therapeutic effect than the control group (42.5%), 82.5% of the patients in the experimental group had higher clinical benefits than the control group (P0.05%), and there was no significant difference between the two groups in the level of serum T cell subsets before treatment, such as: CD3, CD4 / CD8 and CD4 / CD8. After treatment, the CD3 / CD _ 4 / CD _ 8 and CD4 / CD _ 8 in the experimental group were significantly lower than those in the control group (P < 0.05), the incidence of adverse reactions in the experimental group was 32.5, lower than that in the control group (P 0.05), and the ADL score, the somatic function score, the psychological function score and the social function score in the experimental group were higher than those in the control group (P 0.05). Conclusion: the treatment of nasopharyngeal carcinoma combined with Xihuang capsule on the basis of radiotherapy is effective, which can improve the clinical efficacy and reduce the incidence of adverse reactions, which is worth popularizing.
【作者单位】：南阳市中心医院;
【分类号】：R739.63

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